Search and Browse
Download
Enter Data
| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Vasopressin V1a receptor | ||
| Ligand | BDBM50583878 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_2158238 (CHEMBL5042988) | ||
| IC50 | 1.2±n/a nM | ||
| Citation |  Szeleczky, Z; Szakács, Z; Bozó, É; Baska, F; Vukics, K; Lévai, S; Temesvári, K; Vass, E; Béni, Z; Krámos, B; Magdó, I; Szántay, C; Kóti, J; Domány-Kovács, K; Greiner, I; Bata, I Synthesis and Characterization of New V J Med Chem64:10445-10468 (2021) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Vasopressin V1a receptor | |||
| Name: | Vasopressin V1a receptor | ||
| Synonyms: | AVPR V1a | AVPR1 | AVPR1A | Antidiuretic hormone receptor 1a | V1AR_HUMAN | V1aR | VASOPRESSIN V1A | Vascular/hepatic-type arginine vasopressin receptor | Vasopressin V1 receptor | Vasopressin V1a receptor | Vasopressin receptor | ||
| Type: | Receptor | ||
| Mol. Mass.: | 46820.18 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P37288 | ||
| Residue: | 418 | ||
| Sequence: |
| ||
| BDBM50583878 | |||
| n/a | |||
| Name | BDBM50583878 | ||
| Synonyms: | CHEMBL5074709 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C22H23ClN4O2 | ||
| Mol. Mass. | 410.897 | ||
| SMILES | O[C@@H]1Cc2nnc([C@H]3CC[C@@H](CC3)Oc3ccccn3)n2-c2ccc(Cl)cc2C1 |r,wU:7.6,1.0,wD:10.13,(13.29,-32.25,;12.34,-31.15,;12.94,-29.82,;12.31,-28.53,;13.09,-27.19,;12.06,-26.04,;10.65,-26.67,;9.3,-25.9,;7.97,-26.66,;6.64,-25.9,;6.64,-24.35,;7.97,-23.57,;9.3,-24.35,;5.29,-23.58,;3.96,-24.36,;2.61,-23.58,;1.27,-24.36,;1.28,-25.91,;2.63,-26.67,;3.97,-25.9,;10.79,-28.21,;9.65,-29.16,;8.32,-28.45,;7.04,-29.24,;7.09,-30.76,;5.78,-31.58,;8.42,-31.46,;9.69,-30.66,;10.94,-31.56,)| | ||
| Structure | 
| ||