| Reaction Details |
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 | Report a problem with these data |
| Target | Estrogen receptor |
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| Ligand | BDBM50154084 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_306464 (CHEMBL829541) |
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| IC50 | 199±n/a nM |
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| Citation |  Malamas, MS; Manas, ES; McDevitt, RE; Gunawan, I; Xu, ZB; Collini, MD; Miller, CP; Dinh, T; Henderson, RA; Keith, JC; Harris, HA Design and synthesis of aryl diphenolic azoles as potent and selective estrogen receptor-beta ligands. J Med Chem47:5021-40 (2004) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Estrogen receptor |
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| Name: | Estrogen receptor |
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| Synonyms: | ESR1_MOUSE | Esr | Esr1 | Estr | Estra | Estrogen receptor alpha | Nr3a1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 66969.87 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_648798 |
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| Residue: | 599 |
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| Sequence: | MTMTLHTKASGMALLHQIQGNELEPLNRPQLKMPMERALGEVYVDNSKPTVFNYPEGAAY
EFNAAAAAAAAASAPVYGQSGIAYGPGSEAAAFSANSLGAFPQLNSVSPSPLMLLHPPPQ
LSPFLHPHGQQVPYYLENEPSAYAVRDTGPPAFYRSNSDNRRQNGRERLSSSNEKGNMIM
ESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKS
CQACRLRKCYEVGMMKGGIRKDRRGGRMLKHKRQRDDLEGRNEMGASGDMRAANLWPSPL
VIKHTKKNSPALSLTADQMVSALLDAEPPMIYSEYDPSRPFSEASMMGLLTNLADRELVH
MINWAKRVPGFGDLNLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGK
CVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIH
RVLDKITDTLIHLMAKAGLTLQQQHRRLAQLLLILSHIRHMSNKGMEHLYNMKCKNVVPL
YDLLLEMLDAHRLHAPASRMGVPPEEPSQTQLATTSSTSAHSLQTYYIPPEAEGFPNTI
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| BDBM50154084 |
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| n/a |
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| Name | BDBM50154084 |
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| Synonyms: | 7-Bromo-2-(3-fluoro-4-hydroxy-phenyl)-benzooxazol-5-ol | 7-bromo-2-(3-fluoro-4-hydroxyphenyl)benzo[d]oxazol-5-ol | CHEMBL187207 |
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| Type | Small organic molecule |
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| Emp. Form. | C13H7BrFNO3 |
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| Mol. Mass. | 324.102 |
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| SMILES | Oc1cc(Br)c2oc(nc2c1)-c1ccc(O)c(F)c1 |
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| Structure | 
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