| Reaction Details |
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 | Report a problem with these data |
| Target | Cathepsin K |
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| Ligand | BDBM50154178 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_304939 (CHEMBL826968) |
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| IC50 | 37±n/a nM |
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| Citation |  Tavares, FX; Deaton, DN; Miller, LR; Wright, LL Ketoamide-based inhibitors of cysteine protease, cathepsin K: P3 modifications. J Med Chem47:5057-68 (2004) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cathepsin K |
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| Name: | Cathepsin K |
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| Synonyms: | CATK_HUMAN | CTSK | CTSO | CTSO2 | Cathepsin O | Cathepsin O2 | Cathepsin X |
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| Type: | Enzyme |
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| Mol. Mass.: | 36975.68 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P43235 |
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| Residue: | 329 |
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| Sequence: | MWGLKVLLLPVVSFALYPEEILDTHWELWKKTHRKQYNNKVDEISRRLIWEKNLKYISIH
NLEASLGVHTYELAMNHLGDMTSEEVVQKMTGLKVPLSHSRSNDTLYIPEWEGRAPDSVD
YRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSENDGCGGG
YMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNEKALKRAVA
RVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWIIKNSWGE
NWGNKGYILMARNKNNACGIANLASFPKM
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| BDBM50154178 |
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| n/a |
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| Name | BDBM50154178 |
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| Synonyms: | CHEMBL188905 | [1-(1-Phenyl-ethylaminooxalyl)-pentyl]-carbamic acid 1-(thiazol-2-yloxymethyl)-cyclobutylmethyl ester |
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| Type | Small organic molecule |
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| Emp. Form. | C25H33N3O5S |
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| Mol. Mass. | 487.612 |
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| SMILES | CCCC[C@H](NC(=O)OCC1(COc2nccs2)CCC1)C(=O)C(=O)N[C@H](C)c1ccccc1 |
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| Structure | 
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