| Reaction Details |
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 | Report a problem with these data |
| Target | Tyrosine-protein kinase HCK |
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| Ligand | BDBM14322 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_304474 (CHEMBL832690) |
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| EC50 | >1000000±n/a nM |
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| Citation |  Inglis, SR; Stojkoski, C; Branson, KM; Cawthray, JF; Fritz, D; Wiadrowski, E; Pyke, SM; Booker, GW Identification and specificity studies of small-molecule ligands for SH3 protein domains. J Med Chem47:5405-17 (2004) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Tyrosine-protein kinase HCK |
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| Name: | Tyrosine-protein kinase HCK |
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| Synonyms: | HCK | HCK_HUMAN | Hematopoietic cell kinase | Hemopoietic cell kinase | p59-HCK/p60-HCK | p59Hck | p61Hck |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 59600.18 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P08631 |
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| Residue: | 526 |
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| Sequence: | MGGRSSCEDPGCPRDEERAPRMGCMKSKFLQVGGNTFSKTETSASPHCPVYVPDPTSTIK
PGPNSHNSNTPGIREAGSEDIIVVALYDYEAIHHEDLSFQKGDQMVVLEESGEWWKARSL
ATRKEGYIPSNYVARVDSLETEEWFFKGISRKDAERQLLAPGNMLGSFMIRDSETTKGSY
SLSVRDYDPRQGDTVKHYKIRTLDNGGFYISPRSTFSTLQELVDHYKKGNDGLCQKLSVP
CMSSKPQKPWEKDAWEIPRESLKLEKKLGAGQFGEVWMATYNKHTKVAVKTMKPGSMSVE
AFLAEANVMKTLQHDKLVKLHAVVTKEPIYIITEFMAKGSLLDFLKSDEGSKQPLPKLID
FSAQIAEGMAFIEQRNYIHRDLRAANILVSASLVCKIADFGLARVIEDNEYTAREGAKFP
IKWTAPEAINFGSFTIKSDVWSFGILLMEIVTYGRIPYPGMSNPEVIRALERGYRMPRPE
NCPEELYNIMMRCWKNRPEERPTFEYIQSVLDDFYTATESQYQQQP
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| BDBM14322 |
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| n/a |
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| Name | BDBM14322 |
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| Synonyms: | 2-Aminoquinoline 1 | 2-aminoquinoline | CHEMBL61236 | Fragment 19 | Quinolin-2-amine | fragment 2 (J. med. chem.,50,1116) |
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| Type | Small organic molecule |
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| Emp. Form. | C9H8N2 |
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| Mol. Mass. | 144.1732 |
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| SMILES | Nc1ccc2ccccc2n1 |
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| Structure | 
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