| Reaction Details |
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 | Report a problem with these data |
| Target | Tyrosine-protein kinase |
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| Ligand | BDBM14320 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_302256 (CHEMBL829490) |
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| Kd | 650000±n/a nM |
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| Citation |  Inglis, SR; Stojkoski, C; Branson, KM; Cawthray, JF; Fritz, D; Wiadrowski, E; Pyke, SM; Booker, GW Identification and specificity studies of small-molecule ligands for SH3 protein domains. J Med Chem47:5405-17 (2004) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Tyrosine-protein kinase |
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| Name: | Tyrosine-protein kinase |
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| Synonyms: | Q8CFK4_MOUSE | Tec | Tyrosine-protein kinase TEC |
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| Type: | PROTEIN |
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| Mol. Mass.: | 71010.89 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_304473 |
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| Residue: | 608 |
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| Sequence: | MNFNTILEEILIKRSQQKKKTSPLNYKERLFVLTKSVLSYYEGRAEKKYRKGVIDISKIK
CVEIVKNDDGVIPCQNKFPFQVVHDANTLYIFAPSPQSRDRWVKKLKEEIKNNNNIMIKY
HPKFWADGSYQCCRQTEKLAPGCEKYNLFESSIRKTLPPAPEIKKRRPPPPIPPEEENTE
EIVVAMYDFQATEAHDLRLERGQEYIILEKNDLHWWRARDKYGWYCRNTNRSKAEQLLRT
EDKEGGFMVRDSSQPGLYTVSLYTKFGGEGSSGFRHYHIKETATSPKKYYLAEKHAFGSI
PEIIEYHKHNAAGLVTRLRYPVSTKGKNAPTTAGFSYDKWEINPSELTFMRELGSGLFGV
VRLGKWRAQYKVAIKAIREGAMCEEDFIEEAKVMMKLTHPKLVQLYGVCTQQKPIYIVTE
FMERGCLLNFLRQRQGHFSRDMLLSMCQDVCEGMEYLERNSFIHRDLAARNCLVNEAGVV
KVSDFGMARYVLDDQYTSSSGAKFPVKWCPPEVFNYSRFSSKSDVWSFGVLMWEIFTEGR
MPFEKNTNYEVVTMVTRGHRLHRPKLASKYLYEVMLRCWQERPEGRPSFEDLLRTIDELV
ECEETFGR
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| BDBM14320 |
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| n/a |
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| Name | BDBM14320 |
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| Synonyms: | 1-amino-isoquinoline | CHEMBL62083 | Fragment 17 | fragment 1 (J. med. chem.,50,1116) | isoquinolin-1-amine |
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| Type | Small organic molecule |
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| Emp. Form. | C9H8N2 |
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| Mol. Mass. | 144.1732 |
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| SMILES | Nc1nccc2ccccc12 |
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| Structure | 
|
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