| Reaction Details |
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 | Report a problem with these data |
| Target | B1 bradykinin receptor |
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| Ligand | BDBM50156446 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_302734 (CHEMBL876354) |
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| Ki | 34±n/a nM |
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| Citation |  Su, DS; Markowitz, MK; Murphy, KL; Wan, BL; Zrada, MM; Harrell, CM; O'Malley, SS; Hess, JF; Ransom, RW; Chang, RS; Wallace, MA; Raab, CE; Dean, DC; Pettibone, DJ; Freidinger, RM; Bock, MG Development of an efficient and selective radioligand for bradykinin B1 receptor occupancy studies. Bioorg Med Chem Lett14:6045-8 (2004) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| B1 bradykinin receptor |
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| Name: | B1 bradykinin receptor |
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| Synonyms: | B1 BRADYKININ | B1R | B1bkr | BK-1 receptor | BKRB1_RAT | Bdkrb1 | Bkr | Bradykinin B1 receptor | KB1 | Kinin B1 receptor |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 38389.97 |
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| Organism: | RAT |
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| Description: | B1 BRADYKININ BDKRB1 RAT::P97583 |
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| Residue: | 337 |
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| Sequence: | MASEVLLELQPSNRSLQAPANITSCESALEDWDLLYRVLPGFVITICFFGLLGNLLVLSF
FLLPWRQWWWQQRQRQQRLTIAEIYLANLAASDLVFVLGLPFWAENIGNRFNWPFGTDLC
RVVSGVIKANLFVSIFLVVAISQDRYRLLVYPMTSWGYRRRRQAQATCLLIWVAGGLLSI
PTFLLRSVKVVPDLNVSACILLFPHEAWHFARMVELNVLGFLLPVTAIIFFNYHILASLR
GQKEASRTRCGGPKGSKTTGLILTLVASFLVCWCPYHFFAFLDFLVQVRVIQDCSWKEIT
DLGLQLANFFAFVNSCLNPLIYVFAGRLLKTRVLGTL
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| BDBM50156446 |
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| n/a |
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| Name | BDBM50156446 |
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| Synonyms: | CHEMBL359553 | N-{2-[4-(4,5-Dihydro-1H-imidazol-2-yl)-phenyl]-ethyl}-2-[(R)-1-(naphthalene-2-sulfonyl)-3-oxo-1,2,3,4-tetrahydro-quinoxalin-2-yl]-acetamide |
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| Type | Small organic molecule |
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| Emp. Form. | C31H29N5O4S |
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| Mol. Mass. | 567.658 |
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| SMILES | O=C(C[C@H]1N(c2ccccc2NC1=O)S(=O)(=O)c1ccc2ccccc2c1)NCCc1ccc(cc1)C1=NCCN1 |t:41| |
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| Structure | 
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