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TargetBradykinin B1 receptor
LigandBDBM50157516
Substrate/Competitorn/a
Meas. Tech.ChEMBL_429974
IC50 1.4±n/a nM
Citation Kuduk SDNg CFeng DMWai JMChang RSHarrell CMMurphy KLRansom RWReiss DIvarsson MMason GBoyce STang CPrueksaritanont TFreidinger RMPettibone DJBock MG 2,3-diaminopyridine bradykinin B1 receptor antagonists. J Med Chem 47:6439-42 (2004) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Bradykinin B1 receptor
Name:Bradykinin B1 receptor
Synonyms:B1 BRADYKININ | B1 bradykinin receptor | B1R | BK-1 receptor
Type:Enzyme
Mol. Mass.:40508.87
Organism:Homo sapiens (Human)
Description:P46663
Residue:353
Sequence:
MASSWPPLELQSSNQSQLFPQNATACDNAPEAWDLLHRVLPTFIISICFFGLLGNLFVLL
VFLLPRRQLNVAEIYLANLAASDLVFVLGLPFWAENIWNQFNWPFGALLCRVINGVIKAN
LFISIFLVVAISQDRYRVLVHPMASRRQQRRRQARVTCVLIWVVGGLLSIPTFLLRSIQA
VPDLNITACILLLPHEAWHFARIVELNILGFLLPLAAIVFFNYHILASLRTREEVSRTRC
GGRKDSKTTALILTLVVAFLVCWAPYHFFAFLEFLFQVQAVRGCFWEDFIDLGLQLANFF
AFTNSSLNPVIYVFVGRLFRTKVWELYKQCTPKSLAPISSSHRKEIFQLFWRN
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50157516
n/a
NameBDBM50157516
Synonyms:4'-{(R)-1-[3-(2-cyano-acetylamino)-4-methyl-pyridin-2-ylamino]-ethyl}-5-methyl-biphenyl-2-carboxylic acid methyl ester | CHEMBL225133
TypeSmall organic molecule
Emp. Form.C26H26N4O3
Mol. Mass.442.5096
SMILESCOC(=O)c1ccc(C)cc1-c1ccc(cc1)[C@@H](C)Nc1nccc(C)c1NC(=O)CC#N |r|
Structure
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