| Reaction Details |
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 | Report a problem with these data |
| Target | N-lysine methyltransferase SMYD2 |
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| Ligand | BDBM50550527 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2184851 (CHEMBL5096933) |
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| IC50 | 17±n/a nM |
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| Citation |  Lopes, JR; Chiba, DE; Dos Santos, JL HIV latency reversal agents: A potential path for functional cure? Eur J Med Chem213:0 (2021) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| N-lysine methyltransferase SMYD2 |
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| Name: | N-lysine methyltransferase SMYD2 |
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| Synonyms: | HSKM-B | Histone methyltransferase SMYD2 | KMT3C | Lysine N-methyltransferase 3C | N-lysine methyltransferase SMYD2 | SET and MYND domain-containing protein 2 | SET and MYND domain-containing protein 2 (SMYD2) | SMYD2 | SMYD2_HUMAN |
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| Type: | Enzyme |
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| Mol. Mass.: | 49689.57 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q9NRG4 |
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| Residue: | 433 |
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| Sequence: | MRAEGLGGLERFCSPGKGRGLRALQPFQVGDLLFSCPAYAYVLTVNERGNHCEYCFTRKE
GLSKCGRCKQAFYCNVECQKEDWPMHKLECSPMVVFGENWNPSETVRLTARILAKQKIHP
ERTPSEKLLAVKEFESHLDKLDNEKKDLIQSDIAALHHFYSKHLGFPDNDSLVVLFAQVN
CNGFTIEDEELSHLGSAIFPDVALMNHSCCPNVIVTYKGTLAEVRAVQEIKPGEEVFTSY
IDLLYPTEDRNDRLRDSYFFTCECQECTTKDKDKAKVEIRKLSDPPKAEAIRDMVRYARN
VIEEFRRAKHYKSPSELLEICELSQEKMSSVFEDSNVYMLHMMYQAMGVCLYMQDWEGAL
QYGQKIIKPYSKHYPLYSLNVASMWLKLGRLYMGLEHKAAGEKALKKAIAIMEVAHGKDH
PYISEIKQEIESH
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| BDBM50550527 |
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| n/a |
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| Name | BDBM50550527 |
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| Synonyms: | CHEMBL4754902 |
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| Type | Small organic molecule |
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| Emp. Form. | C33H40N6O |
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| Mol. Mass. | 536.7103 |
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| SMILES | O=C(NCCCN1CCCC1)c1cncc(c1)-c1ccccc1N1CCN(CCc2c[nH]c3ccccc23)CC1 |
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| Structure | 
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