| Reaction Details |
|---|
 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 1B |
|---|
| Ligand | BDBM50590649 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_2197403 (CHEMBL5109919) |
|---|
| Ki | 0.010000±n/a nM |
|---|
| Citation |  Fu, H; Rong, J; Chen, Z; Zhou, J; Collier, T; Liang, SH Positron Emission Tomography (PET) Imaging Tracers for Serotonin Receptors. J Med Chem65:10755-10808 (2022) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| 5-hydroxytryptamine receptor 1B |
|---|
| Name: | 5-hydroxytryptamine receptor 1B |
|---|
| Synonyms: | 5-HT1B | 5HT1B_CAVPO | HTR1B |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 43125.84 |
|---|
| Organism: | GUINEA PIG |
|---|
| Description: | 5-HT1B HTR1B GUINEA PIG::O08892 |
|---|
| Residue: | 389 |
|---|
| Sequence: | MGNPEASCTPPAVLGSQTGLPHANVSAPPNNCSAPSHIYQDSIALPWKVLLVVLLALITL
ATTLSNAFVIATVYRTRKLHTPANYLIASLAFTDLLVSILVMPISTMYTVTGRWTLGQAL
CDFWLSSDITCCTASIMHLCVIALDRYWAITDAVGYSAKRTPRRAAGMIALVWVFSICIS
LPPFFWRQAKAEEEVLDCLVNTDHVLYTVYSTGGAFYLPTLLLIALYGRIYVEARSRILK
QTPNKTGKRLTRAQLITDSPGSTSSVTSINSRAPEVPCDSGSPVYVNQVKVRVSDALLEK
KKLMAARERKATKTLGVILGAFIVCWLPFFIISLVMPICKDACWFHMAIFDFFTWLGYLN
SLINPIIYTMSNEDFKQAFHKLIRFKCTT
|
|
|
|---|
| BDBM50590649 |
|---|
| n/a |
|---|
| Name | BDBM50590649 |
|---|
| Synonyms: | CHEMBL5209320 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C26H30N4O4 |
|---|
| Mol. Mass. | 461.5415 |
|---|
| SMILES | Cc1ccc(N2CCN([11CH3])CC2)c2oc(cc(=O)c12)C(=O)Nc1ccc(cc1)N1CCOCC1 |
|---|
| Structure | 
|
|---|
Search and Browse
