| Reaction Details |
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 | Report a problem with these data |
| Target | Integrase |
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| Ligand | BDBM50422695 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_307268 (CHEMBL831653) |
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| IC50 | 1413±n/a nM |
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| Citation |  Verschueren, WG; Dierynck, I; Amssoms, KI; Hu, L; Boonants, PM; Pille, GM; Daeyaert, FF; Hertogs, K; Surleraux, DL; Wigerinck, PB Design and optimization of tricyclic phtalimide analogues as novel inhibitors of HIV-1 integrase. J Med Chem48:1930-40 (2005) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Integrase |
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| Name: | Integrase |
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| Synonyms: | Human immunodeficiency virus type 1 integrase |
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| Type: | PROTEIN |
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| Mol. Mass.: | 32231.48 |
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| Organism: | Human immunodeficiency virus 1 |
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| Description: | ChEMBL_90865 |
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| Residue: | 288 |
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| Sequence: | FLDGIDKAQDEHEKYHSNWRAMASDFNLPPVVAKEIVASCDKCQLKGEAMHGQVDCSPGI
WQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKTIHTDNGSN
FTSTTVKAACWWAGIKQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV
FIHNFKRKGGIGGYSAGERIVDIIATDIQTKELQKQITKIQNFRVYYRDSRDPLWKGPAK
LLWKGEGAVVIQDNSDIKVVPRRKVKIIRDYGKQMAGDDCVASRQDED
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| BDBM50422695 |
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| n/a |
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| Name | BDBM50422695 |
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| Synonyms: | CHEMBL175404 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H13N3O4 |
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| Mol. Mass. | 371.3456 |
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| SMILES | O=c1n(Cc2cccc3ccccc23)c(=O)c2c1c(=O)c1[nH]cc[nH]c1c2=O |
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| Structure | 
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