| Reaction Details |
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 | Report a problem with these data |
| Target | Coagulation factor XIII A chain |
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| Ligand | BDBM50164220 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_304794 (CHEMBL877318) |
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| IC50 | >100000±n/a nM |
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| Citation |  Leung-Toung, R; Tam, TF; Wodzinska, JM; Zhao, Y; Lowrie, J; Simpson, CD; Karimian, K; Spino, M 3-Substituted imidazo[1,2-d][1,2,4]-thiadiazoles: a novel class of factor XIIIa inhibitors. J Med Chem48:2266-9 (2005) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Coagulation factor XIII A chain |
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| Name: | Coagulation factor XIII A chain |
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| Synonyms: | Coagulation factor XIII | F13A | F13A1 | F13A_HUMAN |
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| Type: | PROTEIN |
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| Mol. Mass.: | 83261.29 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1475048 |
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| Residue: | 732 |
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| Sequence: | MSETSRTAFGGRRAVPPNNSNAAEDDLPTVELQGVVPRGVNLQEFLNVTSVHLFKERWDT
NKVDHHTDKYENNKLIVRRGQSFYVQIDFSRPYDPRRDLFRVEYVIGRYPQENKGTYIPV
PIVSELQSGKWGAKIVMREDRSVRLSIQSSPKCIVGKFRMYVAVWTPYGVLRTSRNPETD
TYILFNPWCEDDAVYLDNEKEREEYVLNDIGVIFYGEVNDIKTRSWSYGQFEDGILDTCL
YVMDRAQMDLSGRGNPIKVSRVGSAMVNAKDDEGVLVGSWDNIYAYGVPPSAWTGSVDIL
LEYRSSENPVRYGQCWVFAGVFNTFLRCLGIPARIVTNYFSAHDNDANLQMDIFLEEDGN
VNSKLTKDSVWNYHCWNEAWMTRPDLPVGFGGWQAVDSTPQENSDGMYRCGPASVQAIKH
GHVCFQFDAPFVFAEVNSDLIYITAKKDGTHVVENVDATHIGKLIVTKQIGGDGMMDITD
TYKFQEGQEEERLALETALMYGAKKPLNTEGVMKSRSNVDMDFEVENAVLGKDFKLSITF
RNNSHNRYTITAYLSANITFYTGVPKAEFKKETFDVTLEPLSFKKEAVLIQAGEYMGQLL
EQASLHFFVTARINETRDVLAKQKSTVLTIPEIIIKVRGTQVVGSDMTVTVQFTNPLKET
LRNVWVHLDGPGVTRPMKKMFREIRPNSTVQWEEVCRPWVSGHRKLIASMSSDSLRHVYG
ELDVQIQRRPSM
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| BDBM50164220 |
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| n/a |
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| Name | BDBM50164220 |
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| Synonyms: | CHEMBL192376 | N-Hexyl-2-nitro-benzenesulfonamide |
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| Type | Small organic molecule |
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| Emp. Form. | C12H18N2O4S |
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| Mol. Mass. | 286.347 |
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| SMILES | CCCCCCNS(=O)(=O)c1ccccc1[N+]([O-])=O |
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| Structure | 
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