| Reaction Details |
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 | Report a problem with these data |
| Target | Cytochrome P450 1A2 |
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| Ligand | BDBM50592756 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2205315 (CHEMBL5118023) |
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| Ki | 126500±n/a nM |
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| Citation |  Li, Y; Liu, Y; Chen, Y; Wang, K; Luan, Y Design, synthesis and antitumor activity study of a gemcitabine prodrug conjugated with a HDAC6 inhibitor. Bioorg Med Chem Lett72:0 (2022) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cytochrome P450 1A2 |
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| Name: | Cytochrome P450 1A2 |
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| Synonyms: | CP1A2_RAT | CYPIA2 | Cyp1a-2 | Cyp1a2 | Cytochrome P-448 | Cytochrome P-450d | Cytochrome P450-D |
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| Type: | PROTEIN |
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| Mol. Mass.: | 58273.18 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_1487340 |
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| Residue: | 513 |
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| Sequence: | MAFSQYISLAPELLLATAIFCLVFWVLRGTRTQVPKGLKSPPGPWGLPFIGHMLTLGKNP
HLSLTKLSQQYGDVLQIRIGSTPVVVLSGLNTIKQALVKQGDDFKGRPDLYSFTLITNGK
SMTFNPDSGPVWAARRRLAQDALKSFSIASDPTSVSSCYLEEHVSKEANHLISKFQKLMA
EVGHFEPVNQVVESVANVIGAMCFGKNFPRKSEEMLNLVKSSKDFVENVTSGNAVDFFPV
LRYLPNPALKRFKNFNDNFVLFLQKTVQEHYQDFNKNSIQDITGALFKHSENYKDNGGLI
PQEKIVNIVNDIFGAGFETVTTAIFWSILLLVTEPKVQRKIHEELDTVIGRDRQPRLSDR
PQLPYLEAFILEIYRYTSFVPFTIPHSTTRDTSLNGFHIPKECCIFINQWQVNHDEKQWK
DPFVFRPERFLTNDNTAIDKTLSEKVMLFGLGKRRCIGEIPAKWEVFLFLAILLHQLEFT
VPPGVKVDLTPSYGLTMKPRTCEHVQAWPRFSK
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| BDBM50592756 |
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| n/a |
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| Name | BDBM50592756 |
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| Synonyms: | CHEMBL5182450 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H39F2N3O5 |
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| Mol. Mass. | 487.5804 |
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| SMILES | CCCCCCCCCCCCCCC(=O)Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)C2(F)F)c(=O)n1 |r| |
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| Structure | 
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