| Reaction Details |
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 | Report a problem with these data |
| Target | Appetite-regulating hormone |
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| Ligand | BDBM50593263 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2207825 (CHEMBL5120533) |
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| EC50 | 1.6±n/a nM |
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| Citation |  Li, HZ; Shao, XX; Shou, LL; Li, N; Liu, YL; Xu, ZG; Guo, ZY Development of Esterase-Resistant and Highly Active Ghrelin Analogs via Thiol-Ene Click Chemistry. ACS Med Chem Lett13:1655-1662 (2022) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Appetite-regulating hormone |
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| Name: | Appetite-regulating hormone |
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| Synonyms: | GHRL | GHRL_HUMAN | Ghrelin | Ghrelin-27 | Ghrelin-28 | Growth hormone secretagogue | Growth hormone-releasing peptide | MTLRP | Motilin-related peptide | Obestatin | Protein M46 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 12908.57 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_790253 |
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| Residue: | 117 |
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| Sequence: | MPSPGTVCSLLLLGMLWLDLAMAGSSFLSPEHQRVQQRKESKKPPAKLQPRALAGWLRPE
DGGQAEGAEDELEVRFNAPFDVGIKLSGVQYQQHSQALGKFLQDILWEEAKEAPADK
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| BDBM50593263 |
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| n/a |
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| Name | BDBM50593263 |
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| Synonyms: | CHEMBL5174499 |
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| Type | Small organic molecule |
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| Emp. Form. | C150H253N47O40S |
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| Mol. Mass. | 3386.97 |
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| SMILES | CCCCCCCCCSC[C@H](NC(=O)[C@H](CO)NC(=O)CN)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(O)=O |r| |
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| Structure | 
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