| Reaction Details |
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 | Report a problem with these data |
| Target | Procathepsin L |
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| Ligand | BDBM50167297 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_302893 (CHEMBL830209) |
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| Ki | 1500±n/a nM |
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| Citation |  Barrett, DG; Deaton, DN; Hassell, AM; McFadyen, RB; Miller, AB; Miller, LR; Payne, JA; Shewchuk, LM; Willard, DH; Wright, LL Acyclic cyanamide-based inhibitors of cathepsin K. Bioorg Med Chem Lett15:3039-43 (2005) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Procathepsin L |
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| Name: | Procathepsin L |
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| Synonyms: | CATL1_HUMAN | CTSL | CTSL CTSL1 | CTSL1 | Cathepsin L | Cathepsin L1 | Cathepsin L1 heavy chain | Cathepsin L1 light chain | MEP | Major excreted protein | cathepsin L preproprotein |
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| Type: | Enzyme |
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| Mol. Mass.: | 37557.19 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Purchased from Calbiochem (San Diego, CA). |
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| Residue: | 333 |
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| Sequence: | MNPTLILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIE
LHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRSVDW
REKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNG
GLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVA
TVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKN
SWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV
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| BDBM50167297 |
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| n/a |
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| Name | BDBM50167297 |
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| Synonyms: | (Cyano-methyl-amino)-acetic acid (S)-2-cyclohexyl-1-methyl-ethyl ester | CHEMBL189149 |
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| Type | Small organic molecule |
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| Emp. Form. | C13H22N2O2 |
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| Mol. Mass. | 238.326 |
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| SMILES | C[C@@H](CC1CCCCC1)OC(=O)CN(C)C#N |
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| Structure | 
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