| Reaction Details |
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 | Report a problem with these data |
| Target | L-lactate dehydrogenase B chain |
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| Ligand | BDBM50594014 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2210642 (CHEMBL5123591) |
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| IC50 | 1100±n/a nM |
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| Citation |  Moya-Garzon, MD; Rodriguez-Rodriguez, B; Martin-Higueras, C; Franco-Montalban, F; Fernandes, MX; Gomez-Vidal, JA; Pey, AL; Salido, E; Diaz-Gavilan, M New salicylic acid derivatives, double inhibitors of glycolate oxidase and lactate dehydrogenase, as effective agents decreasing oxalate production. Eur J Med Chem237:0 (2022) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| L-lactate dehydrogenase B chain |
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| Name: | L-lactate dehydrogenase B chain |
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| Synonyms: | L-lactate dehydrogenase B | L-lactate dehydrogenase B chain | LDH heart subunit | LDH-B | LDH-H | LDHB | LDHB_HUMAN | Lactate dehydrogenase B (LDHB) | Renal carcinoma antigen NY-REN-46 |
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| Type: | Oxidoreductase; homotetramer |
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| Mol. Mass.: | 36635.55 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 334 |
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| Sequence: | MATLKEKLIAPVAEEEATVPNNKITVVGVGQVGMACAISILGKSLADELALVDVLEDKLK
GEMMDLQHGSLFLQTPKIVADKDYSVTANSKIVVVTAGVRQQEGESRLNLVQRNVNVFKF
IIPQIVKYSPDCIIIVVSNPVDILTYVTWKLSGLPKHRVIGSGCNLDSARFRYLMAEKLG
IHPSSCHGWILGEHGDSSVAVWSGVNVAGVSLQELNPEMGTDNDSENWKEVHKMVVESAY
EVIKLKGYTNWAIGLSVADLIESMLKNLSRIHPVSTMVKGMYGIENEVFLSLPCILNARG
LTSVINQKLKDDEVAQLKKSADTLWDIQKDLKDL
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| BDBM50594014 |
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| n/a |
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| Name | BDBM50594014 |
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| Synonyms: | CHEMBL5182027 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H17BrN2O4 |
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| Mol. Mass. | 405.243 |
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| SMILES | N.OC(=O)c1cc(ccc1O)-c1ccc(CNc2ccc(Br)cc2)o1 |
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| Structure | 
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