| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Androgen receptor |
|---|
| Ligand | BDBM50170578 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_322421 (CHEMBL873543) |
|---|
| IC50 | 820±n/a nM |
|---|
| Citation |  Hosoda, S; Tanatani, A; Wakabayashi, K; Nakano, Y; Miyachi, H; Nagasawa, K; Hashimoto, Y Ligands with dual vitamin D3-agonistic and androgen-antagonistic activities. Bioorg Med Chem Lett15:4327-31 (2005) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Androgen receptor |
|---|
| Name: | Androgen receptor |
|---|
| Synonyms: | ANDR_MOUSE | Ar | Nr3c4 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 98196.62 |
|---|
| Organism: | Mus musculus |
|---|
| Description: | ChEMBL_945930 |
|---|
| Residue: | 899 |
|---|
| Sequence: | MEVQLGLGRVYPRPPSKTYRGAFQNLFQSVREAIQNPGPRHPEAANIAPPGACLQQRQET
SPRRRRRQQHTEDGSPQAHIRGPTGYLALEEEQQPSQQQAASEGHPESSCLPEPGAATAP
GKGLPQQPPAPPDQDDSAAPSTLSLLGPTFPGLSSCSADIKDILNEAGTMQLLQQQQQQQ
QHQQQHQQHQQQQEVISEGSSARAREATGAPSSSKDSYLGGNSTISDSAKELCKAVSVSM
GLGVEALEHLSPGEQLRGDCMYASLLGGPPAVRPTPCAPLPECKGLPLDEGPGKSTEETA
EYSSFKGGYAKGLEGESLGCSGSSEAGSSGTLEIPSSLSLYKSGALDEAAAYQNRDYYNF
PLALSGPPHPPPPTHPHARIKLENPLDYGSAWAAAAAQCRYGDLGSLHGGSVAGPSTGSP
PATTSSSWHTLFTAEEGQLYGPGGGGGSSSPSDAGPVAPYGYTRPPQGLTSQESDYSASE
VWYPGGVVNRVPYPSPNCVKSEMGPWMENYSGPYGDMRLDSTRDHVLPIDYYFPPQKTCL
ICGDEASGCHYGALTCGSCKVFFKRAAEGKQKYLCASRNDCTIDKFRRKNCPSCRLRKCY
EAGMTLGARKLKKLGNLKLQEEGENSNAGSPTEDPSQKMTVSHIEGYECQPIFLNVLEAI
EPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKWAKALPGFRNLHVDDQMAVIQYS
WMGLMVFAMGWRSFTNVNSRMLYFAPDLVFNEYRMHKSRMYSQCVRMRHLSQEFGWLQIT
PQEFLCMKALLLFSIIPVDGLKNQKFFDELRMNYIKELDRIIACKRKNPTSCSRRFYQLT
KLLDSVQPIARELHQFTFDLLIKSHMVSVDFPEMMAEIISVQVPKILSGKVKPIYFHTQ
|
|
|
|---|
| BDBM50170578 |
|---|
| n/a |
|---|
| Name | BDBM50170578 |
|---|
| Synonyms: | 1-(4-{1-Ethyl-1-[4-(3-hydroxy-3-methyl-butylamino)-3-methyl-phenyl]-propyl}-2-methyl-phenoxy)-3,3-dimethyl-butan-2-one | CHEMBL197548 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C30H45NO3 |
|---|
| Mol. Mass. | 467.6832 |
|---|
| SMILES | CCC(CC)(c1ccc(NCCC(C)(C)O)c(C)c1)c1ccc(OCC(=O)C(C)(C)C)c(C)c1 |
|---|
| Structure | 
|
|---|
Search and Browse
