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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Metabotropic glutamate receptor 1 | ||
| Ligand | BDBM50171313 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_303740 (CHEMBL829783) | ||
| Ki | 0.87±n/a nM | ||
| Citation |  Huang, Y; Narendran, R; Bischoff, F; Guo, N; Zhu, Z; Bae, SA; Lesage, AS; Laruelle, M A positron emission tomography radioligand for the in vivo labeling of metabotropic glutamate 1 receptor: (3-ethyl-2-[11C]methyl-6-quinolinyl)(cis- 4-methoxycyclohexyl)methanone. J Med Chem48:5096-9 (2005) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Metabotropic glutamate receptor 1 | |||
| Name: | Metabotropic glutamate receptor 1 | ||
| Synonyms: | GRM1_RAT | Gprc1a | Grm1 | Metabotropic Glutamate 1a | Metabotropic glutamate receptor | Metabotropic glutamate receptor 1 | Mglur1 | metabotropic glutamate 1 | metabotropic glutamate 1/5-D | metabotropic glutamate 1/DA | metabotropic glutamate receptor 1 isoform alpha precursor | ||
| Type: | Enzyme Catalytic Domain | ||
| Mol. Mass.: | 133240.47 | ||
| Organism: | RAT | ||
| Description: | metabotropic glutamate 1/2 0 RAT::P23385 | ||
| Residue: | 1199 | ||
| Sequence: |
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| BDBM50171313 | |||
| n/a | |||
| Name | BDBM50171313 | ||
| Synonyms: | (3-Ethyl-2-methyl-quinolin-6-yl)-(4-methoxy-cyclohexyl)-methanone | CHEMBL188906 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C20H25NO2 | ||
| Mol. Mass. | 311.418 | ||
| SMILES | CCc1cc2cc(ccc2nc1C)C(=O)[C@@H]1CC[C@@H](CC1)OC |wU:15.16,18.23,(20.81,-1.24,;19.47,-.49,;18.14,-1.27,;16.81,-.5,;15.48,-1.27,;14.15,-.5,;12.82,-1.27,;12.82,-2.81,;14.15,-3.58,;15.48,-2.81,;16.81,-3.58,;18.14,-2.81,;19.48,-3.58,;11.48,-.5,;11.48,1.04,;10.02,-1.13,;8.73,-.29,;7.33,-1.17,;7.33,-2.71,;8.69,-3.48,;10.02,-2.69,;6,-3.48,;4.67,-2.71,)| | ||
| Structure | 
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