| Reaction Details |
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 | Report a problem with these data |
| Target | Proteasome subunit beta type-1 |
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| Ligand | BDBM50596498 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2220561 (CHEMBL5133895) |
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| IC50 | 19000±n/a nM |
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| Citation |  Nishimura, S; Hitora, Y; Kawahara, T; Tanabe, M; Ogata, E; Kato, H; Srikoon, P; Watanabe, T; Tsukamoto, S Cell-based screening of extracts of natural sources to search for inhibitors of the ubiquitin-proteasome system and identification of proteasome inhibitors from the fungus Remotididymella sp. Bioorg Med Chem Lett59:0 (2022) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Proteasome subunit beta type-1 |
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| Name: | Proteasome subunit beta type-1 |
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| Synonyms: | PSB1_HUMAN | PSC5 | PSMB1 | Proteasome component C5 | Proteasome subunit beta type-1/beta type-5 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 26493.62 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1366691 |
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| Residue: | 241 |
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| Sequence: | MLSSTAMYSAPGRDLGMEPHRAAGPLQLRFSPYVFNGGTILAIAGEDFAIVASDTRLSEG
FSIHTRDSPKCYKLTDKTVIGCSGFHGDCLTLTKIIEARLKMYKHSNNKAMTTGAIAAML
STILYSRRFFPYYVYNIIGGLDEEGKGAVYSFDPVGSYQRDSFKAGGSASAMLQPLLDNQ
VGFKNMQNVEHVPLSLDRAMRLVKDVFISAAERDVYTGDALRICIVTKEGIREETVSLRK
D
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| BDBM50596498 |
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| n/a |
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| Name | BDBM50596498 |
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| Synonyms: | CHEMBL5177192 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H28O6 |
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| Mol. Mass. | 412.4755 |
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| SMILES | CCC(C)\C=C(/C)C1=Cc2cc3C=C(OC)C(O)(CC(C)=O)C(=O)c3c(O)c2CO1 |t:7,12| |
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| Structure | 
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