| Reaction Details |
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 | Report a problem with these data |
| Target | 1-acyl-sn-glycerol-3-phosphate acyltransferase beta |
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| Ligand | BDBM50172956 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_321473 (CHEMBL880414) |
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| IC50 | 40±n/a nM |
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| Citation |  Hong, F; Hollenback, D; Singer, JW; Klein, P Diamino-C,N-diarylpyridine positional isomers as inhibitors of lysophosphatidic acid acyltransferase-beta. Bioorg Med Chem Lett15:4703-7 (2005) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| 1-acyl-sn-glycerol-3-phosphate acyltransferase beta |
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| Name: | 1-acyl-sn-glycerol-3-phosphate acyltransferase beta |
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| Synonyms: | 1-acylglycerol-3-phosphate O-acyltransferase beta | AGPAT2 | PLCB_HUMAN |
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| Type: | PROTEIN |
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| Mol. Mass.: | 30924.09 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_321473 |
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| Residue: | 278 |
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| Sequence: | MELWPCLAAALLLLLLLVQLSRAAEFYAKVALYCALCFTVSAVASLVCLLRHGGRTVENM
SIIGWFVRSFKYFYGLRFEVRDPRRLQEARPCVIVSNHQSILDMMGLMEVLPERCVQIAK
RELLFLGPVGLIMYLGGVFFINRQRSSTAMTVMADLGERMVRENLKVWIYPEGTRNDNGD
LLPFKKGAFYLAVQAQVPIVPVVYSSFSSFYNTKKKFFTSGTVTVQVLEAIPTSGLTAAD
VPALVDTCHRAMRTTFLHISKTPQENGATAGSGVQPAQ
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| BDBM50172956 |
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| n/a |
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| Name | BDBM50172956 |
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| Synonyms: | 4-(5-Chloro-2-methoxy-phenyl)-N-(4-chloro-phenyl)-pyridine-2,6-diamine | CHEMBL193874 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H15Cl2N3O |
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| Mol. Mass. | 360.237 |
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| SMILES | COc1ccc(Cl)cc1-c1cc(N)nc(Nc2ccc(Cl)cc2)c1 |
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| Structure | 
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