Found 65 hits with Last Name = 'singer' and Initial = 'jw' Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
1-acyl-sn-glycerol-3-phosphate acyltransferase beta
(Homo sapiens (Human)) | BDBM50144730
(6-(5-Chloro-2-ethoxy-phenyl)-N*4*-(4-nitro-phenyl)...)Show SMILES CCOc1ccc(Cl)cc1-c1cc(Nc2ccc(cc2)[N+]([O-])=O)nc(N)n1 Show InChI InChI=1S/C18H16ClN5O3/c1-2-27-16-8-3-11(19)9-14(16)15-10-17(23-18(20)22-15)21-12-4-6-13(7-5-12)24(25)26/h3-10H,2H2,1H3,(H3,20,21,22,23) | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
Cell Therapeutics, Inc
Curated by ChEMBL
| Assay Description
Inhibitory activity against Lysophosphatidic acid acyltransferase-beta expressed in Sf9 insect cell membranes |
Bioorg Med Chem Lett 14: 2303-8 (2004)
Article DOI: 10.1016/j.bmcl.2004.01.104
BindingDB Entry DOI: 10.7270/Q2Q23ZPH |
More data for this
Ligand-Target Pair | |
1-acyl-sn-glycerol-3-phosphate acyltransferase beta
(Homo sapiens (Human)) | BDBM50144700
(6-(5-Bromo-2-ethoxy-phenyl)-N*4*-(4-chloro-phenyl)...)Show InChI InChI=1S/C18H16BrClN4O/c1-2-25-16-8-3-11(19)9-14(16)15-10-17(24-18(21)23-15)22-13-6-4-12(20)5-7-13/h3-10H,2H2,1H3,(H3,21,22,23,24) | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
Cell Therapeutics, Inc
Curated by ChEMBL
| Assay Description
Inhibitory activity against Lysophosphatidic acid acyltransferase-beta expressed in Sf9 insect cell membranes |
Bioorg Med Chem Lett 14: 2303-8 (2004)
Article DOI: 10.1016/j.bmcl.2004.01.104
BindingDB Entry DOI: 10.7270/Q2Q23ZPH |
More data for this
Ligand-Target Pair | |
1-acyl-sn-glycerol-3-phosphate acyltransferase beta
(Homo sapiens (Human)) | BDBM50144706
(6-(5-Chloro-2-ethoxy-phenyl)-N*4*-(4-chloro-phenyl...)Show InChI InChI=1S/C18H16Cl2N4O/c1-2-25-16-8-5-12(20)9-14(16)15-10-17(24-18(21)23-15)22-13-6-3-11(19)4-7-13/h3-10H,2H2,1H3,(H3,21,22,23,24) | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
Cell Therapeutics, Inc.
Curated by ChEMBL
| Assay Description
Inhibitory activity against Lysophosphatidic acid acyltransferase-beta enzyme overexpressed in Sf9 insect cell membrane |
Bioorg Med Chem Lett 15: 4703-7 (2005)
Article DOI: 10.1016/j.bmcl.2005.07.055
BindingDB Entry DOI: 10.7270/Q29G5MB2 |
More data for this
Ligand-Target Pair | |
1-acyl-sn-glycerol-3-phosphate acyltransferase beta
(Homo sapiens (Human)) | BDBM50144706
(6-(5-Chloro-2-ethoxy-phenyl)-N*4*-(4-chloro-phenyl...)Show InChI InChI=1S/C18H16Cl2N4O/c1-2-25-16-8-5-12(20)9-14(16)15-10-17(24-18(21)23-15)22-13-6-3-11(19)4-7-13/h3-10H,2H2,1H3,(H3,21,22,23,24) | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
Cell Therapeutics, Inc
Curated by ChEMBL
| Assay Description
Inhibitory activity against Lysophosphatidic acid acyltransferase-beta expressed in Sf9 insect cell membranes |
Bioorg Med Chem Lett 14: 2303-8 (2004)
Article DOI: 10.1016/j.bmcl.2004.01.104
BindingDB Entry DOI: 10.7270/Q2Q23ZPH |
More data for this
Ligand-Target Pair | |
1-acyl-sn-glycerol-3-phosphate acyltransferase beta
(Homo sapiens (Human)) | BDBM50144723
(4-[2-Amino-6-(5-bromo-2-ethoxy-phenyl)-pyrimidin-4...)Show SMILES CCOc1ccc(Br)cc1-c1cc(Nc2ccc(cc2)C#N)nc(N)n1 Show InChI InChI=1S/C19H16BrN5O/c1-2-26-17-8-5-13(20)9-15(17)16-10-18(25-19(22)24-16)23-14-6-3-12(11-21)4-7-14/h3-10H,2H2,1H3,(H3,22,23,24,25) | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
Cell Therapeutics, Inc
Curated by ChEMBL
| Assay Description
Inhibitory activity against Lysophosphatidic acid acyltransferase-beta expressed in Sf9 insect cell membranes |
Bioorg Med Chem Lett 14: 2303-8 (2004)
Article DOI: 10.1016/j.bmcl.2004.01.104
BindingDB Entry DOI: 10.7270/Q2Q23ZPH |
More data for this
Ligand-Target Pair | |
1-acyl-sn-glycerol-3-phosphate acyltransferase beta
(Homo sapiens (Human)) | BDBM50144696
(6-(5-Bromo-2-methyl-phenyl)-N*4*-(4-bromo-phenyl)-...)Show InChI InChI=1S/C17H14Br2N4/c1-10-2-3-12(19)8-14(10)15-9-16(23-17(20)22-15)21-13-6-4-11(18)5-7-13/h2-9H,1H3,(H3,20,21,22,23) | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a | n/a |
Cell Therapeutics, Inc
Curated by ChEMBL
| Assay Description
Inhibitory activity against Lysophosphatidic acid acyltransferase-beta expressed in Sf9 insect cell membranes |
Bioorg Med Chem Lett 14: 2303-8 (2004)
Article DOI: 10.1016/j.bmcl.2004.01.104
BindingDB Entry DOI: 10.7270/Q2Q23ZPH |
More data for this
Ligand-Target Pair | |
1-acyl-sn-glycerol-3-phosphate acyltransferase beta
(Homo sapiens (Human)) | BDBM50144694
(CHEMBL307716 | N*4*-(4-Chloro-phenyl)-6-(2,5-dichl...)Show InChI InChI=1S/C16H11Cl3N4/c17-9-1-4-11(5-2-9)21-15-8-14(22-16(20)23-15)12-7-10(18)3-6-13(12)19/h1-8H,(H3,20,21,22,23) | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
Cell Therapeutics, Inc
Curated by ChEMBL
| Assay Description
Inhibitory activity against Lysophosphatidic acid acyltransferase-beta expressed in Sf9 insect cell membranes |
Bioorg Med Chem Lett 14: 2303-8 (2004)
Article DOI: 10.1016/j.bmcl.2004.01.104
BindingDB Entry DOI: 10.7270/Q2Q23ZPH |
More data for this
Ligand-Target Pair | |
1-acyl-sn-glycerol-3-phosphate acyltransferase beta
(Homo sapiens (Human)) | BDBM50144714
(6-(5-Chloro-2-methyl-phenyl)-N*4*-(4-chloro-phenyl...)Show InChI InChI=1S/C17H14Cl2N4/c1-10-2-3-12(19)8-14(10)15-9-16(23-17(20)22-15)21-13-6-4-11(18)5-7-13/h2-9H,1H3,(H3,20,21,22,23) | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 22 | n/a | n/a | n/a | n/a | n/a | n/a |
Cell Therapeutics, Inc
Curated by ChEMBL
| Assay Description
Inhibitory activity against Lysophosphatidic acid acyltransferase-beta expressed in Sf9 insect cell membranes |
Bioorg Med Chem Lett 14: 2303-8 (2004)
Article DOI: 10.1016/j.bmcl.2004.01.104
BindingDB Entry DOI: 10.7270/Q2Q23ZPH |
More data for this
Ligand-Target Pair | |
1-acyl-sn-glycerol-3-phosphate acyltransferase beta
(Homo sapiens (Human)) | BDBM50144702
(6-(5-Chloro-2-ethoxy-phenyl)-N*4*-(1H-indazol-6-yl...)Show SMILES CCOc1ccc(Cl)cc1-c1cc(Nc2ccc3c[nH]nc3c2)nc(N)n1 Show InChI InChI=1S/C19H17ClN6O/c1-2-27-17-6-4-12(20)7-14(17)16-9-18(25-19(21)24-16)23-13-5-3-11-10-22-26-15(11)8-13/h3-10H,2H2,1H3,(H,22,26)(H3,21,23,24,25) | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 24 | n/a | n/a | n/a | n/a | n/a | n/a |
Cell Therapeutics, Inc
Curated by ChEMBL
| Assay Description
Inhibitory activity against Lysophosphatidic acid acyltransferase-beta expressed in Sf9 insect cell membranes |
Bioorg Med Chem Lett 14: 2303-8 (2004)
Article DOI: 10.1016/j.bmcl.2004.01.104
BindingDB Entry DOI: 10.7270/Q2Q23ZPH |
More data for this
Ligand-Target Pair | |
1-acyl-sn-glycerol-3-phosphate acyltransferase beta
(Homo sapiens (Human)) | BDBM50144715
(2-{4-[2-Amino-6-(5-chloro-2-ethoxy-phenyl)-pyrimid...)Show SMILES CCOc1ccc(Cl)cc1-c1cc(Nc2ccc(CCO)cc2)nc(N)n1 Show InChI InChI=1S/C20H21ClN4O2/c1-2-27-18-8-5-14(21)11-16(18)17-12-19(25-20(22)24-17)23-15-6-3-13(4-7-15)9-10-26/h3-8,11-12,26H,2,9-10H2,1H3,(H3,22,23,24,25) | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 28 | n/a | n/a | n/a | n/a | n/a | n/a |
Cell Therapeutics, Inc
Curated by ChEMBL
| Assay Description
Inhibitory activity against Lysophosphatidic acid acyltransferase-beta expressed in Sf9 insect cell membranes |
Bioorg Med Chem Lett 14: 2303-8 (2004)
Article DOI: 10.1016/j.bmcl.2004.01.104
BindingDB Entry DOI: 10.7270/Q2Q23ZPH |
More data for this
Ligand-Target Pair | |
1-acyl-sn-glycerol-3-phosphate acyltransferase beta
(Homo sapiens (Human)) | BDBM50144725
(CHEMBL424605 | N*4*-(4-Bromo-phenyl)-6-(5-chloro-2...)Show InChI InChI=1S/C17H14BrClN4O/c1-24-15-7-4-11(19)8-13(15)14-9-16(23-17(20)22-14)21-12-5-2-10(18)3-6-12/h2-9H,1H3,(H3,20,21,22,23) | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 28 | n/a | n/a | n/a | n/a | n/a | n/a |
Cell Therapeutics, Inc
Curated by ChEMBL
| Assay Description
Inhibitory activity against Lysophosphatidic acid acyltransferase-beta expressed in Sf9 insect cell membranes |
Bioorg Med Chem Lett 14: 2303-8 (2004)
Article DOI: 10.1016/j.bmcl.2004.01.104
BindingDB Entry DOI: 10.7270/Q2Q23ZPH |
More data for this
Ligand-Target Pair | |
1-acyl-sn-glycerol-3-phosphate acyltransferase beta
(Homo sapiens (Human)) | BDBM50144727
(6-(5-Bromo-2-methyl-phenyl)-N*4*-(4-chloro-phenyl)...)Show InChI InChI=1S/C17H14BrClN4/c1-10-2-3-11(18)8-14(10)15-9-16(23-17(20)22-15)21-13-6-4-12(19)5-7-13/h2-9H,1H3,(H3,20,21,22,23) | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 31 | n/a | n/a | n/a | n/a | n/a | n/a |
Cell Therapeutics, Inc
Curated by ChEMBL
| Assay Description
Inhibitory activity against Lysophosphatidic acid acyltransferase-beta expressed in Sf9 insect cell membranes |
Bioorg Med Chem Lett 14: 2303-8 (2004)
Article DOI: 10.1016/j.bmcl.2004.01.104
BindingDB Entry DOI: 10.7270/Q2Q23ZPH |
More data for this
Ligand-Target Pair | |
1-acyl-sn-glycerol-3-phosphate acyltransferase beta
(Homo sapiens (Human)) | BDBM50144698
(CHEMBL73376 | N*4*-(4-Bromo-phenyl)-6-(5-chloro-2-...)Show InChI InChI=1S/C17H14BrClN4/c1-10-2-5-12(19)8-14(10)15-9-16(23-17(20)22-15)21-13-6-3-11(18)4-7-13/h2-9H,1H3,(H3,20,21,22,23) | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 34 | n/a | n/a | n/a | n/a | n/a | n/a |
Cell Therapeutics, Inc
Curated by ChEMBL
| Assay Description
Inhibitory activity against Lysophosphatidic acid acyltransferase-beta expressed in Sf9 insect cell membranes |
Bioorg Med Chem Lett 14: 2303-8 (2004)
Article DOI: 10.1016/j.bmcl.2004.01.104
BindingDB Entry DOI: 10.7270/Q2Q23ZPH |
More data for this
Ligand-Target Pair | |
1-acyl-sn-glycerol-3-phosphate acyltransferase beta
(Homo sapiens (Human)) | BDBM50144709
(1-{4-[2-Amino-6-(5-bromo-2-ethoxy-phenyl)-pyrimidi...)Show SMILES CCOc1ccc(Br)cc1-c1cc(Nc2ccc(cc2)C(C)=O)nc(N)n1 Show InChI InChI=1S/C20H19BrN4O2/c1-3-27-18-9-6-14(21)10-16(18)17-11-19(25-20(22)24-17)23-15-7-4-13(5-8-15)12(2)26/h4-11H,3H2,1-2H3,(H3,22,23,24,25) | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 34 | n/a | n/a | n/a | n/a | n/a | n/a |
Cell Therapeutics, Inc
Curated by ChEMBL
| Assay Description
Inhibitory activity against Lysophosphatidic acid acyltransferase-beta expressed in Sf9 insect cell membranes |
Bioorg Med Chem Lett 14: 2303-8 (2004)
Article DOI: 10.1016/j.bmcl.2004.01.104
BindingDB Entry DOI: 10.7270/Q2Q23ZPH |
More data for this
Ligand-Target Pair | |
1-acyl-sn-glycerol-3-phosphate acyltransferase beta
(Homo sapiens (Human)) | BDBM50172956
(4-(5-Chloro-2-methoxy-phenyl)-N-(4-chloro-phenyl)-...)Show InChI InChI=1S/C18H15Cl2N3O/c1-24-16-7-4-13(20)10-15(16)11-8-17(21)23-18(9-11)22-14-5-2-12(19)3-6-14/h2-10H,1H3,(H3,21,22,23) | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | n/a |
Cell Therapeutics, Inc.
Curated by ChEMBL
| Assay Description
Inhibitory activity against Lysophosphatidic acid acyltransferase-beta enzyme overexpressed in Sf9 insect cell membrane |
Bioorg Med Chem Lett 15: 4703-7 (2005)
Article DOI: 10.1016/j.bmcl.2005.07.055
BindingDB Entry DOI: 10.7270/Q29G5MB2 |
More data for this
Ligand-Target Pair | |
1-acyl-sn-glycerol-3-phosphate acyltransferase beta
(Homo sapiens (Human)) | BDBM50172955
(4-(5-Chloro-2-ethoxy-phenyl)-N-(4-chloro-phenyl)-p...)Show InChI InChI=1S/C19H17Cl2N3O/c1-2-25-17-8-5-14(21)11-16(17)12-9-18(22)24-19(10-12)23-15-6-3-13(20)4-7-15/h3-11H,2H2,1H3,(H3,22,23,24) | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a |
Cell Therapeutics, Inc.
Curated by ChEMBL
| Assay Description
Inhibitory activity against Lysophosphatidic acid acyltransferase-beta enzyme overexpressed in Sf9 insect cell membrane |
Bioorg Med Chem Lett 15: 4703-7 (2005)
Article DOI: 10.1016/j.bmcl.2005.07.055
BindingDB Entry DOI: 10.7270/Q29G5MB2 |
More data for this
Ligand-Target Pair | |
1-acyl-sn-glycerol-3-phosphate acyltransferase beta
(Homo sapiens (Human)) | BDBM50172950
(4-[6-Amino-4-(5-chloro-2-ethoxy-phenyl)-pyridin-2-...)Show SMILES CCOc1ccc(Cl)cc1-c1cc(N)nc(Nc2ccc(C=O)cc2)c1 Show InChI InChI=1S/C20H18ClN3O2/c1-2-26-18-8-5-15(21)11-17(18)14-9-19(22)24-20(10-14)23-16-6-3-13(12-25)4-7-16/h3-12H,2H2,1H3,(H3,22,23,24) | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a |
Cell Therapeutics, Inc.
Curated by ChEMBL
| Assay Description
Inhibitory activity against Lysophosphatidic acid acyltransferase-beta enzyme overexpressed in Sf9 insect cell membrane |
Bioorg Med Chem Lett 15: 4703-7 (2005)
Article DOI: 10.1016/j.bmcl.2005.07.055
BindingDB Entry DOI: 10.7270/Q29G5MB2 |
More data for this
Ligand-Target Pair | |
1-acyl-sn-glycerol-3-phosphate acyltransferase beta
(Homo sapiens (Human)) | BDBM50144724
(6-(5-Chloro-2-methoxy-phenyl)-N*4*-(4-chloro-pheny...)Show InChI InChI=1S/C17H14Cl2N4O/c1-24-15-7-4-11(19)8-13(15)14-9-16(23-17(20)22-14)21-12-5-2-10(18)3-6-12/h2-9H,1H3,(H3,20,21,22,23) | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 54 | n/a | n/a | n/a | n/a | n/a | n/a |
Cell Therapeutics, Inc.
Curated by ChEMBL
| Assay Description
Inhibitory activity against Lysophosphatidic acid acyltransferase-beta enzyme overexpressed in Sf9 insect cell membrane |
Bioorg Med Chem Lett 15: 4703-7 (2005)
Article DOI: 10.1016/j.bmcl.2005.07.055
BindingDB Entry DOI: 10.7270/Q29G5MB2 |
More data for this
Ligand-Target Pair | |
1-acyl-sn-glycerol-3-phosphate acyltransferase beta
(Homo sapiens (Human)) | BDBM50144724
(6-(5-Chloro-2-methoxy-phenyl)-N*4*-(4-chloro-pheny...)Show InChI InChI=1S/C17H14Cl2N4O/c1-24-15-7-4-11(19)8-13(15)14-9-16(23-17(20)22-14)21-12-5-2-10(18)3-6-12/h2-9H,1H3,(H3,20,21,22,23) | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 54 | n/a | n/a | n/a | n/a | n/a | n/a |
Cell Therapeutics, Inc
Curated by ChEMBL
| Assay Description
Inhibitory activity against Lysophosphatidic acid acyltransferase-beta expressed in Sf9 insect cell membranes |
Bioorg Med Chem Lett 14: 2303-8 (2004)
Article DOI: 10.1016/j.bmcl.2004.01.104
BindingDB Entry DOI: 10.7270/Q2Q23ZPH |
More data for this
Ligand-Target Pair | |
1-acyl-sn-glycerol-3-phosphate acyltransferase beta
(Homo sapiens (Human)) | BDBM50172951
(6-(5-Chloro-2-methoxy-phenyl)-N-(4-chloro-phenyl)-...)Show InChI InChI=1S/C16H13Cl2N5O/c1-24-13-7-4-10(18)8-12(13)14-21-15(19)23-16(22-14)20-11-5-2-9(17)3-6-11/h2-8H,1H3,(H3,19,20,21,22,23) | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 70 | n/a | n/a | n/a | n/a | n/a | n/a |
Cell Therapeutics, Inc.
Curated by ChEMBL
| Assay Description
Inhibitory activity against Lysophosphatidic acid acyltransferase-beta enzyme overexpressed in Sf9 insect cell membrane |
Bioorg Med Chem Lett 15: 4703-7 (2005)
Article DOI: 10.1016/j.bmcl.2005.07.055
BindingDB Entry DOI: 10.7270/Q29G5MB2 |
More data for this
Ligand-Target Pair | |
1-acyl-sn-glycerol-3-phosphate acyltransferase beta
(Homo sapiens (Human)) | BDBM50172951
(6-(5-Chloro-2-methoxy-phenyl)-N-(4-chloro-phenyl)-...)Show InChI InChI=1S/C16H13Cl2N5O/c1-24-13-7-4-10(18)8-12(13)14-21-15(19)23-16(22-14)20-11-5-2-9(17)3-6-11/h2-8H,1H3,(H3,19,20,21,22,23) | Reactome pathway
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| n/a | n/a | 70 | n/a | n/a | n/a | n/a | n/a | n/a |
Cell Therapeutics, Inc.
Curated by ChEMBL
| Assay Description
Inhibitory activity against Lysophosphatidic acid acyltransferase-beta enzyme overexpressed in Sf9 insect cell membrane |
Bioorg Med Chem Lett 15: 4703-7 (2005)
Article DOI: 10.1016/j.bmcl.2005.07.055
BindingDB Entry DOI: 10.7270/Q29G5MB2 |
More data for this
Ligand-Target Pair | |
1-acyl-sn-glycerol-3-phosphate acyltransferase beta
(Homo sapiens (Human)) | BDBM50144722
(CHEMBL75522 | {4-[2-Amino-6-(5-chloro-2-ethoxy-phe...)Show InChI InChI=1S/C19H19ClN4O2/c1-2-26-17-8-5-13(20)9-15(17)16-10-18(24-19(21)23-16)22-14-6-3-12(11-25)4-7-14/h3-10,25H,2,11H2,1H3,(H3,21,22,23,24) | Reactome pathway
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| n/a | n/a | 75 | n/a | n/a | n/a | n/a | n/a | n/a |
Cell Therapeutics, Inc
Curated by ChEMBL
| Assay Description
Inhibitory activity against Lysophosphatidic acid acyltransferase-beta expressed in Sf9 insect cell membranes |
Bioorg Med Chem Lett 14: 2303-8 (2004)
Article DOI: 10.1016/j.bmcl.2004.01.104
BindingDB Entry DOI: 10.7270/Q2Q23ZPH |
More data for this
Ligand-Target Pair | |
1-acyl-sn-glycerol-3-phosphate acyltransferase beta
(Homo sapiens (Human)) | BDBM50144729
(6-(5-Chloro-2-methoxy-phenyl)-N*4*-(1H-indazol-6-y...)Show SMILES COc1ccc(Cl)cc1-c1cc(Nc2ccc3c[nH]nc3c2)nc(N)n1 Show InChI InChI=1S/C18H15ClN6O/c1-26-16-5-3-11(19)6-13(16)15-8-17(24-18(20)23-15)22-12-4-2-10-9-21-25-14(10)7-12/h2-9H,1H3,(H,21,25)(H3,20,22,23,24) | Reactome pathway
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| n/a | n/a | 80 | n/a | n/a | n/a | n/a | n/a | n/a |
Cell Therapeutics, Inc
Curated by ChEMBL
| Assay Description
Inhibitory activity against Lysophosphatidic acid acyltransferase-beta expressed in Sf9 insect cell membranes |
Bioorg Med Chem Lett 14: 2303-8 (2004)
Article DOI: 10.1016/j.bmcl.2004.01.104
BindingDB Entry DOI: 10.7270/Q2Q23ZPH |
More data for this
Ligand-Target Pair | |
1-acyl-sn-glycerol-3-phosphate acyltransferase beta
(Homo sapiens (Human)) | BDBM50144711
(1-{4-[2-Amino-6-(5-bromo-2-ethoxy-phenyl)-pyrimidi...)Show SMILES CCOc1ccc(Br)cc1-c1cc(Nc2ccc(cc2)C(C)N=O)nc(N)n1 Show InChI InChI=1S/C20H20BrN5O2/c1-3-28-18-9-6-14(21)10-16(18)17-11-19(25-20(22)24-17)23-15-7-4-13(5-8-15)12(2)26-27/h4-12H,3H2,1-2H3,(H3,22,23,24,25) | Reactome pathway
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| n/a | n/a | 84 | n/a | n/a | n/a | n/a | n/a | n/a |
Cell Therapeutics, Inc
Curated by ChEMBL
| Assay Description
Inhibitory activity against Lysophosphatidic acid acyltransferase-beta expressed in Sf9 insect cell membranes |
Bioorg Med Chem Lett 14: 2303-8 (2004)
Article DOI: 10.1016/j.bmcl.2004.01.104
BindingDB Entry DOI: 10.7270/Q2Q23ZPH |
More data for this
Ligand-Target Pair | |
1-acyl-sn-glycerol-3-phosphate acyltransferase beta
(Homo sapiens (Human)) | BDBM50144734
(4-[2-Amino-6-(5-bromo-2-ethoxy-phenyl)-pyrimidin-4...)Show SMILES CCOc1ccc(Br)cc1-c1cc(Nc2ccc(cc2)C(=O)NO)nc(N)n1 Show InChI InChI=1S/C19H18BrN5O3/c1-2-28-16-8-5-12(20)9-14(16)15-10-17(24-19(21)23-15)22-13-6-3-11(4-7-13)18(26)25-27/h3-10,27H,2H2,1H3,(H,25,26)(H3,21,22,23,24) | Reactome pathway
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| n/a | n/a | 88 | n/a | n/a | n/a | n/a | n/a | n/a |
Cell Therapeutics, Inc
Curated by ChEMBL
| Assay Description
Inhibitory activity against Lysophosphatidic acid acyltransferase-beta expressed in Sf9 insect cell membranes |
Bioorg Med Chem Lett 14: 2303-8 (2004)
Article DOI: 10.1016/j.bmcl.2004.01.104
BindingDB Entry DOI: 10.7270/Q2Q23ZPH |
More data for this
Ligand-Target Pair | |
1-acyl-sn-glycerol-3-phosphate acyltransferase beta
(Homo sapiens (Human)) | BDBM50144719
(6-(5-Bromo-2-ethoxy-phenyl)-N*4*-(4-dihydroxyboron...)Show SMILES CCOc1ccc(Br)cc1-c1cc(Nc2ccc(cc2)B(O)O)nc(N)n1 Show InChI InChI=1S/C18H18BBrN4O3/c1-2-27-16-8-5-12(20)9-14(16)15-10-17(24-18(21)23-15)22-13-6-3-11(4-7-13)19(25)26/h3-10,25-26H,2H2,1H3,(H3,21,22,23,24) | Reactome pathway
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| n/a | n/a | 91 | n/a | n/a | n/a | n/a | n/a | n/a |
Cell Therapeutics, Inc
Curated by ChEMBL
| Assay Description
Inhibitory activity against Lysophosphatidic acid acyltransferase-beta expressed in Sf9 insect cell membranes |
Bioorg Med Chem Lett 14: 2303-8 (2004)
Article DOI: 10.1016/j.bmcl.2004.01.104
BindingDB Entry DOI: 10.7270/Q2Q23ZPH |
More data for this
Ligand-Target Pair | |
1-acyl-sn-glycerol-3-phosphate acyltransferase beta
(Homo sapiens (Human)) | BDBM50172952
(CHEMBL193588 | {4-[6-Amino-4-(5-chloro-2-ethoxy-ph...)Show InChI InChI=1S/C20H20ClN3O2/c1-2-26-18-8-5-15(21)11-17(18)14-9-19(22)24-20(10-14)23-16-6-3-13(12-25)4-7-16/h3-11,25H,2,12H2,1H3,(H3,22,23,24) | Reactome pathway
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| n/a | n/a | 99 | n/a | n/a | n/a | n/a | n/a | n/a |
Cell Therapeutics, Inc.
Curated by ChEMBL
| Assay Description
Inhibitory activity against Lysophosphatidic acid acyltransferase-beta enzyme overexpressed in Sf9 insect cell membrane |
Bioorg Med Chem Lett 15: 4703-7 (2005)
Article DOI: 10.1016/j.bmcl.2005.07.055
BindingDB Entry DOI: 10.7270/Q29G5MB2 |
More data for this
Ligand-Target Pair | |
1-acyl-sn-glycerol-3-phosphate acyltransferase beta
(Homo sapiens (Human)) | BDBM50144699
(6-(5-Bromo-2-ethoxy-phenyl)-N*4*-phenyl-pyrimidine...)Show InChI InChI=1S/C18H17BrN4O/c1-2-24-16-9-8-12(19)10-14(16)15-11-17(23-18(20)22-15)21-13-6-4-3-5-7-13/h3-11H,2H2,1H3,(H3,20,21,22,23) | Reactome pathway
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| n/a | n/a | 120 | n/a | n/a | n/a | n/a | n/a | n/a |
Cell Therapeutics, Inc
Curated by ChEMBL
| Assay Description
Inhibitory activity against Lysophosphatidic acid acyltransferase-beta expressed in Sf9 insect cell membranes |
Bioorg Med Chem Lett 14: 2303-8 (2004)
Article DOI: 10.1016/j.bmcl.2004.01.104
BindingDB Entry DOI: 10.7270/Q2Q23ZPH |
More data for this
Ligand-Target Pair | |
1-acyl-sn-glycerol-3-phosphate acyltransferase beta
(Homo sapiens (Human)) | BDBM50172949
(6-(5-Chloro-2-ethoxy-phenyl)-N-(4-chloro-phenyl)-[...)Show InChI InChI=1S/C17H15Cl2N5O/c1-2-25-14-8-5-11(19)9-13(14)15-22-16(20)24-17(23-15)21-12-6-3-10(18)4-7-12/h3-9H,2H2,1H3,(H3,20,21,22,23,24) | Reactome pathway
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| n/a | n/a | 140 | n/a | n/a | n/a | n/a | n/a | n/a |
Cell Therapeutics, Inc.
Curated by ChEMBL
| Assay Description
Inhibitory activity against Lysophosphatidic acid acyltransferase-beta enzyme overexpressed in Sf9 insect cell membrane |
Bioorg Med Chem Lett 15: 4703-7 (2005)
Article DOI: 10.1016/j.bmcl.2005.07.055
BindingDB Entry DOI: 10.7270/Q29G5MB2 |
More data for this
Ligand-Target Pair | |
1-acyl-sn-glycerol-3-phosphate acyltransferase beta
(Homo sapiens (Human)) | BDBM50172949
(6-(5-Chloro-2-ethoxy-phenyl)-N-(4-chloro-phenyl)-[...)Show InChI InChI=1S/C17H15Cl2N5O/c1-2-25-14-8-5-11(19)9-13(14)15-22-16(20)24-17(23-15)21-12-6-3-10(18)4-7-12/h3-9H,2H2,1H3,(H3,20,21,22,23,24) | Reactome pathway
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| n/a | n/a | 140 | n/a | n/a | n/a | n/a | n/a | n/a |
Cell Therapeutics, Inc.
Curated by ChEMBL
| Assay Description
Inhibitory activity against Lysophosphatidic acid acyltransferase-beta enzyme overexpressed in Sf9 insect cell membrane |
Bioorg Med Chem Lett 15: 4703-7 (2005)
Article DOI: 10.1016/j.bmcl.2005.07.055
BindingDB Entry DOI: 10.7270/Q29G5MB2 |
More data for this
Ligand-Target Pair | |
1-acyl-sn-glycerol-3-phosphate acyltransferase beta
(Homo sapiens (Human)) | BDBM50144701
(6-(5-Chloro-2-methyl-phenyl)-N*4*-(4-trifluorometh...)Show SMILES Cc1ccc(Cl)cc1-c1cc(Nc2ccc(cc2)C(F)(F)F)nc(N)n1 Show InChI InChI=1S/C18H14ClF3N4/c1-10-2-5-12(19)8-14(10)15-9-16(26-17(23)25-15)24-13-6-3-11(4-7-13)18(20,21)22/h2-9H,1H3,(H3,23,24,25,26) | Reactome pathway
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| n/a | n/a | 140 | n/a | n/a | n/a | n/a | n/a | n/a |
Cell Therapeutics, Inc
Curated by ChEMBL
| Assay Description
Inhibitory activity against Lysophosphatidic acid acyltransferase-beta expressed in Sf9 insect cell membranes |
Bioorg Med Chem Lett 14: 2303-8 (2004)
Article DOI: 10.1016/j.bmcl.2004.01.104
BindingDB Entry DOI: 10.7270/Q2Q23ZPH |
More data for this
Ligand-Target Pair | |
1-acyl-sn-glycerol-3-phosphate acyltransferase beta
(Homo sapiens (Human)) | BDBM50144733
(CHEMBL73947 | N*4*-(4-Chloro-phenyl)-6-(5-fluoro-2...)Show InChI InChI=1S/C17H14ClFN4/c1-10-2-5-12(19)8-14(10)15-9-16(23-17(20)22-15)21-13-6-3-11(18)4-7-13/h2-9H,1H3,(H3,20,21,22,23) | Reactome pathway
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| n/a | n/a | 150 | n/a | n/a | n/a | n/a | n/a | n/a |
Cell Therapeutics, Inc
Curated by ChEMBL
| Assay Description
Inhibitory activity against Lysophosphatidic acid acyltransferase-beta expressed in Sf9 insect cell membranes |
Bioorg Med Chem Lett 14: 2303-8 (2004)
Article DOI: 10.1016/j.bmcl.2004.01.104
BindingDB Entry DOI: 10.7270/Q2Q23ZPH |
More data for this
Ligand-Target Pair | |
1-acyl-sn-glycerol-3-phosphate acyltransferase beta
(Homo sapiens (Human)) | BDBM50144712
(CHEMBL75714 | {4-[2-Amino-6-(5-bromo-2-ethoxy-phen...)Show SMILES CCOc1ccc(Br)cc1-c1cc(Nc2ccc(CC(O)=O)cc2)nc(N)n1 Show InChI InChI=1S/C20H19BrN4O3/c1-2-28-17-8-5-13(21)10-15(17)16-11-18(25-20(22)24-16)23-14-6-3-12(4-7-14)9-19(26)27/h3-8,10-11H,2,9H2,1H3,(H,26,27)(H3,22,23,24,25) | Reactome pathway
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| n/a | n/a | 210 | n/a | n/a | n/a | n/a | n/a | n/a |
Cell Therapeutics, Inc
Curated by ChEMBL
| Assay Description
Inhibitory activity against Lysophosphatidic acid acyltransferase-beta expressed in Sf9 insect cell membranes |
Bioorg Med Chem Lett 14: 2303-8 (2004)
Article DOI: 10.1016/j.bmcl.2004.01.104
BindingDB Entry DOI: 10.7270/Q2Q23ZPH |
More data for this
Ligand-Target Pair | |
1-acyl-sn-glycerol-3-phosphate acyltransferase beta
(Homo sapiens (Human)) | BDBM50144707
(3-{4-[2-Amino-6-(5-chloro-2-ethoxy-phenyl)-pyrimid...)Show SMILES CCOc1ccc(Cl)cc1-c1cc(Nc2ccc(CCCO)cc2)nc(N)n1 Show InChI InChI=1S/C21H23ClN4O2/c1-2-28-19-10-7-15(22)12-17(19)18-13-20(26-21(23)25-18)24-16-8-5-14(6-9-16)4-3-11-27/h5-10,12-13,27H,2-4,11H2,1H3,(H3,23,24,25,26) | Reactome pathway
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| n/a | n/a | 230 | n/a | n/a | n/a | n/a | n/a | n/a |
Cell Therapeutics, Inc
Curated by ChEMBL
| Assay Description
Inhibitory activity against Lysophosphatidic acid acyltransferase-beta expressed in Sf9 insect cell membranes |
Bioorg Med Chem Lett 14: 2303-8 (2004)
Article DOI: 10.1016/j.bmcl.2004.01.104
BindingDB Entry DOI: 10.7270/Q2Q23ZPH |
More data for this
Ligand-Target Pair | |
1-acyl-sn-glycerol-3-phosphate acyltransferase beta
(Homo sapiens (Human)) | BDBM50172959
(4-(5-Chloro-2-methoxy-phenyl)-N-p-tolyl-pyridine-2...)Show InChI InChI=1S/C19H18ClN3O/c1-12-3-6-15(7-4-12)22-19-10-13(9-18(21)23-19)16-11-14(20)5-8-17(16)24-2/h3-11H,1-2H3,(H3,21,22,23) | Reactome pathway
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| n/a | n/a | 240 | n/a | n/a | n/a | n/a | n/a | n/a |
Cell Therapeutics, Inc.
Curated by ChEMBL
| Assay Description
Inhibitory activity against Lysophosphatidic acid acyltransferase-beta enzyme overexpressed in Sf9 insect cell membrane |
Bioorg Med Chem Lett 15: 4703-7 (2005)
Article DOI: 10.1016/j.bmcl.2005.07.055
BindingDB Entry DOI: 10.7270/Q29G5MB2 |
More data for this
Ligand-Target Pair | |
1-acyl-sn-glycerol-3-phosphate acyltransferase beta
(Homo sapiens (Human)) | BDBM50172948
(4-[6-Amino-4-(5-chloro-2-methoxy-phenyl)-pyridin-2...)Show InChI InChI=1S/C19H16ClN3O2/c1-25-17-7-4-14(20)10-16(17)13-8-18(21)23-19(9-13)22-15-5-2-12(11-24)3-6-15/h2-11H,1H3,(H3,21,22,23) | Reactome pathway
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| n/a | n/a | 260 | n/a | n/a | n/a | n/a | n/a | n/a |
Cell Therapeutics, Inc.
Curated by ChEMBL
| Assay Description
Inhibitory activity against Lysophosphatidic acid acyltransferase-beta enzyme overexpressed in Sf9 insect cell membrane |
Bioorg Med Chem Lett 15: 4703-7 (2005)
Article DOI: 10.1016/j.bmcl.2005.07.055
BindingDB Entry DOI: 10.7270/Q29G5MB2 |
More data for this
Ligand-Target Pair | |
1-acyl-sn-glycerol-3-phosphate acyltransferase beta
(Homo sapiens (Human)) | BDBM50144721
(2-{4-[2-Amino-6-(5-bromo-2-ethoxy-phenyl)-pyrimidi...)Show SMILES CCOc1ccc(Br)cc1-c1cc(Nc2ccc(CC(=O)NO)cc2)nc(N)n1 Show InChI InChI=1S/C20H20BrN5O3/c1-2-29-17-8-5-13(21)10-15(17)16-11-18(25-20(22)24-16)23-14-6-3-12(4-7-14)9-19(27)26-28/h3-8,10-11,28H,2,9H2,1H3,(H,26,27)(H3,22,23,24,25) | Reactome pathway
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| n/a | n/a | 400 | n/a | n/a | n/a | n/a | n/a | n/a |
Cell Therapeutics, Inc
Curated by ChEMBL
| Assay Description
Inhibitory activity against Lysophosphatidic acid acyltransferase-beta expressed in Sf9 insect cell membranes |
Bioorg Med Chem Lett 14: 2303-8 (2004)
Article DOI: 10.1016/j.bmcl.2004.01.104
BindingDB Entry DOI: 10.7270/Q2Q23ZPH |
More data for this
Ligand-Target Pair | |
1-acyl-sn-glycerol-3-phosphate acyltransferase beta
(Homo sapiens (Human)) | BDBM50144726
(2-[2-Amino-6-(4-chloro-phenylamino)-pyrimidin-4-yl...)Show InChI InChI=1S/C16H12BrClN4O/c17-9-1-6-14(23)12(7-9)13-8-15(22-16(19)21-13)20-11-4-2-10(18)3-5-11/h1-8,23H,(H3,19,20,21,22) | Reactome pathway
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| n/a | n/a | 450 | n/a | n/a | n/a | n/a | n/a | n/a |
Cell Therapeutics, Inc
Curated by ChEMBL
| Assay Description
Inhibitory activity against Lysophosphatidic acid acyltransferase-beta expressed in Sf9 insect cell membranes |
Bioorg Med Chem Lett 14: 2303-8 (2004)
Article DOI: 10.1016/j.bmcl.2004.01.104
BindingDB Entry DOI: 10.7270/Q2Q23ZPH |
More data for this
Ligand-Target Pair | |
1-acyl-sn-glycerol-3-phosphate acyltransferase beta
(Homo sapiens (Human)) | BDBM50172954
(4-(5-Chloro-2-ethoxy-phenyl)-N-p-tolyl-pyridine-2,...)Show InChI InChI=1S/C20H20ClN3O/c1-3-25-18-9-6-15(21)12-17(18)14-10-19(22)24-20(11-14)23-16-7-4-13(2)5-8-16/h4-12H,3H2,1-2H3,(H3,22,23,24) | Reactome pathway
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| n/a | n/a | 490 | n/a | n/a | n/a | n/a | n/a | n/a |
Cell Therapeutics, Inc.
Curated by ChEMBL
| Assay Description
Inhibitory activity against Lysophosphatidic acid acyltransferase-beta enzyme overexpressed in Sf9 insect cell membrane |
Bioorg Med Chem Lett 15: 4703-7 (2005)
Article DOI: 10.1016/j.bmcl.2005.07.055
BindingDB Entry DOI: 10.7270/Q29G5MB2 |
More data for this
Ligand-Target Pair | |
1-acyl-sn-glycerol-3-phosphate acyltransferase beta
(Homo sapiens (Human)) | BDBM50144705
(CHEMBL77790 | {4-[2-Amino-6-(5-chloro-2-ethoxy-phe...)Show SMILES CCOc1ccc(Cl)cc1-c1cc(Nc2ccc(CC(O)=O)cc2)nc(N)n1 Show InChI InChI=1S/C20H19ClN4O3/c1-2-28-17-8-5-13(21)10-15(17)16-11-18(25-20(22)24-16)23-14-6-3-12(4-7-14)9-19(26)27/h3-8,10-11H,2,9H2,1H3,(H,26,27)(H3,22,23,24,25) | Reactome pathway
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| n/a | n/a | 580 | n/a | n/a | n/a | n/a | n/a | n/a |
Cell Therapeutics, Inc
Curated by ChEMBL
| Assay Description
Inhibitory activity against Lysophosphatidic acid acyltransferase-beta expressed in Sf9 insect cell membranes |
Bioorg Med Chem Lett 14: 2303-8 (2004)
Article DOI: 10.1016/j.bmcl.2004.01.104
BindingDB Entry DOI: 10.7270/Q2Q23ZPH |
More data for this
Ligand-Target Pair | |
1-acyl-sn-glycerol-3-phosphate acyltransferase beta
(Homo sapiens (Human)) | BDBM50144710
(CHEMBL305688 | N*4*-(3-Bromo-phenyl)-6-(5-chloro-2...)Show InChI InChI=1S/C17H14BrClN4/c1-10-5-6-12(19)8-14(10)15-9-16(23-17(20)22-15)21-13-4-2-3-11(18)7-13/h2-9H,1H3,(H3,20,21,22,23) | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 610 | n/a | n/a | n/a | n/a | n/a | n/a |
Cell Therapeutics, Inc
Curated by ChEMBL
| Assay Description
Inhibitory activity against Lysophosphatidic acid acyltransferase-beta expressed in Sf9 insect cell membranes |
Bioorg Med Chem Lett 14: 2303-8 (2004)
Article DOI: 10.1016/j.bmcl.2004.01.104
BindingDB Entry DOI: 10.7270/Q2Q23ZPH |
More data for this
Ligand-Target Pair | |
1-acyl-sn-glycerol-3-phosphate acyltransferase beta
(Homo sapiens (Human)) | BDBM50144718
(6-(5-Chloro-2-ethoxy-phenyl)-N*4*-(3-nitro-phenyl)...)Show SMILES CCOc1ccc(Cl)cc1-c1cc(Nc2cccc(c2)[N+]([O-])=O)nc(N)n1 Show InChI InChI=1S/C18H16ClN5O3/c1-2-27-16-7-6-11(19)8-14(16)15-10-17(23-18(20)22-15)21-12-4-3-5-13(9-12)24(25)26/h3-10H,2H2,1H3,(H3,20,21,22,23) | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 640 | n/a | n/a | n/a | n/a | n/a | n/a |
Cell Therapeutics, Inc
Curated by ChEMBL
| Assay Description
Inhibitory activity against Lysophosphatidic acid acyltransferase-beta expressed in Sf9 insect cell membranes |
Bioorg Med Chem Lett 14: 2303-8 (2004)
Article DOI: 10.1016/j.bmcl.2004.01.104
BindingDB Entry DOI: 10.7270/Q2Q23ZPH |
More data for this
Ligand-Target Pair | |
1-acyl-sn-glycerol-3-phosphate acyltransferase beta
(Homo sapiens (Human)) | BDBM50144708
(3-[2-Amino-6-(5-bromo-2-ethoxy-phenyl)-pyrimidin-4...)Show SMILES CCOc1ccc(Br)cc1-c1cc(Nc2cccc(c2)C#N)nc(N)n1 Show InChI InChI=1S/C19H16BrN5O/c1-2-26-17-7-6-13(20)9-15(17)16-10-18(25-19(22)24-16)23-14-5-3-4-12(8-14)11-21/h3-10H,2H2,1H3,(H3,22,23,24,25) | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 720 | n/a | n/a | n/a | n/a | n/a | n/a |
Cell Therapeutics, Inc
Curated by ChEMBL
| Assay Description
Inhibitory activity against Lysophosphatidic acid acyltransferase-beta expressed in Sf9 insect cell membranes |
Bioorg Med Chem Lett 14: 2303-8 (2004)
Article DOI: 10.1016/j.bmcl.2004.01.104
BindingDB Entry DOI: 10.7270/Q2Q23ZPH |
More data for this
Ligand-Target Pair | |
1-acyl-sn-glycerol-3-phosphate acyltransferase beta
(Homo sapiens (Human)) | BDBM50144720
(4-[2-Amino-6-(5-bromo-2-ethoxy-phenyl)-pyrimidin-4...)Show SMILES CCOc1ccc(Br)cc1-c1cc(Nc2ccc(cc2)C(N)=O)nc(N)n1 Show InChI InChI=1S/C19H18BrN5O2/c1-2-27-16-8-5-12(20)9-14(16)15-10-17(25-19(22)24-15)23-13-6-3-11(4-7-13)18(21)26/h3-10H,2H2,1H3,(H2,21,26)(H3,22,23,24,25) | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
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| CHEMBL
PC cid
PC sid
UniChem
Patents
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| Article
PubMed
| n/a | n/a | 750 | n/a | n/a | n/a | n/a | n/a | n/a |
Cell Therapeutics, Inc
Curated by ChEMBL
| Assay Description
Inhibitory activity against Lysophosphatidic acid acyltransferase-beta expressed in Sf9 insect cell membranes |
Bioorg Med Chem Lett 14: 2303-8 (2004)
Article DOI: 10.1016/j.bmcl.2004.01.104
BindingDB Entry DOI: 10.7270/Q2Q23ZPH |
More data for this
Ligand-Target Pair | |
1-acyl-sn-glycerol-3-phosphate acyltransferase beta
(Homo sapiens (Human)) | BDBM50144695
(6-(5-Chloro-2-methoxy-phenyl)-N*2*-(1H-indazol-6-y...)Show SMILES COc1ccc(Cl)cc1-c1cc(N)nc(Nc2ccc3c[nH]nc3c2)n1 Show InChI InChI=1S/C18H15ClN6O/c1-26-16-5-3-11(19)6-13(16)15-8-17(20)24-18(23-15)22-12-4-2-10-9-21-25-14(10)7-12/h2-9H,1H3,(H,21,25)(H3,20,22,23,24) | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
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| CHEMBL
PC cid
PC sid
UniChem
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| Article
PubMed
| n/a | n/a | 800 | n/a | n/a | n/a | n/a | n/a | n/a |
Cell Therapeutics, Inc
Curated by ChEMBL
| Assay Description
Inhibitory activity against Lysophosphatidic acid acyltransferase-beta expressed in Sf9 insect cell membranes |
Bioorg Med Chem Lett 14: 2303-8 (2004)
Article DOI: 10.1016/j.bmcl.2004.01.104
BindingDB Entry DOI: 10.7270/Q2Q23ZPH |
More data for this
Ligand-Target Pair | |
1-acyl-sn-glycerol-3-phosphate acyltransferase beta
(Homo sapiens (Human)) | BDBM50144703
(1-{4-[2-Amino-6-(5-bromo-2-ethoxy-phenyl)-pyrimidi...)Show SMILES CCOc1ccc(Br)cc1-c1cc(Nc2ccc(cc2)C(\C)=N/OC)nc(N)n1 Show InChI InChI=1S/C21H22BrN5O2/c1-4-29-19-10-7-15(22)11-17(19)18-12-20(26-21(23)25-18)24-16-8-5-14(6-9-16)13(2)27-28-3/h5-12H,4H2,1-3H3,(H3,23,24,25,26)/b27-13- | Reactome pathway
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UniChem
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PubMed
| n/a | n/a | 970 | n/a | n/a | n/a | n/a | n/a | n/a |
Cell Therapeutics, Inc
Curated by ChEMBL
| Assay Description
Inhibitory activity against Lysophosphatidic acid acyltransferase-beta expressed in Sf9 insect cell membranes |
Bioorg Med Chem Lett 14: 2303-8 (2004)
Article DOI: 10.1016/j.bmcl.2004.01.104
BindingDB Entry DOI: 10.7270/Q2Q23ZPH |
More data for this
Ligand-Target Pair | |
1-acyl-sn-glycerol-3-phosphate acyltransferase beta
(Homo sapiens (Human)) | BDBM50144732
(CHEMBL75791 | N*4*-(4-Chloro-phenyl)-6-phenyl-pyri...)Show InChI InChI=1S/C16H13ClN4/c17-12-6-8-13(9-7-12)19-15-10-14(20-16(18)21-15)11-4-2-1-3-5-11/h1-10H,(H3,18,19,20,21) | Reactome pathway
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UniProtKB/SwissProt
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GoogleScholar
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| CHEMBL
PC cid
PC sid
UniChem
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| Article
PubMed
| n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Cell Therapeutics, Inc
Curated by ChEMBL
| Assay Description
Inhibitory activity against Lysophosphatidic acid acyltransferase-beta expressed in Sf9 insect cell membranes |
Bioorg Med Chem Lett 14: 2303-8 (2004)
Article DOI: 10.1016/j.bmcl.2004.01.104
BindingDB Entry DOI: 10.7270/Q2Q23ZPH |
More data for this
Ligand-Target Pair | |
1-acyl-sn-glycerol-3-phosphate acyltransferase beta
(Homo sapiens (Human)) | BDBM50144713
(6-(5-Chloro-2-methoxy-phenyl)-N*2*-(4-chloro-pheny...)Show InChI InChI=1S/C17H14Cl2N4O/c1-24-15-7-4-11(19)8-13(15)14-9-16(20)23-17(22-14)21-12-5-2-10(18)3-6-12/h2-9H,1H3,(H3,20,21,22,23) | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Cell Therapeutics, Inc.
Curated by ChEMBL
| Assay Description
Inhibitory activity against Lysophosphatidic acid acyltransferase-beta enzyme overexpressed in Sf9 insect cell membrane |
Bioorg Med Chem Lett 15: 4703-7 (2005)
Article DOI: 10.1016/j.bmcl.2005.07.055
BindingDB Entry DOI: 10.7270/Q29G5MB2 |
More data for this
Ligand-Target Pair | |
1-acyl-sn-glycerol-3-phosphate acyltransferase beta
(Homo sapiens (Human)) | BDBM50144713
(6-(5-Chloro-2-methoxy-phenyl)-N*2*-(4-chloro-pheny...)Show InChI InChI=1S/C17H14Cl2N4O/c1-24-15-7-4-11(19)8-13(15)14-9-16(20)23-17(22-14)21-12-5-2-10(18)3-6-12/h2-9H,1H3,(H3,20,21,22,23) | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 2.05E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Cell Therapeutics, Inc.
Curated by ChEMBL
| Assay Description
Inhibitory activity against Lysophosphatidic acid acyltransferase-beta enzyme overexpressed in Sf9 insect cell membrane |
Bioorg Med Chem Lett 15: 4703-7 (2005)
Article DOI: 10.1016/j.bmcl.2005.07.055
BindingDB Entry DOI: 10.7270/Q29G5MB2 |
More data for this
Ligand-Target Pair | |
1-acyl-sn-glycerol-3-phosphate acyltransferase beta
(Homo sapiens (Human)) | BDBM50144716
(2-(5-Chloro-2-methoxy-phenyl)-N-(1H-indazol-6-yl)-...)Show SMILES COc1ccc(Cl)cc1-c1nc(N)cc(Nc2ccc3c[nH]nc3c2)n1 Show InChI InChI=1S/C18H15ClN6O/c1-26-15-5-3-11(19)6-13(15)18-23-16(20)8-17(24-18)22-12-4-2-10-9-21-25-14(10)7-12/h2-9H,1H3,(H,21,25)(H3,20,22,23,24) | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| n/a | n/a | 2.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Cell Therapeutics, Inc
Curated by ChEMBL
| Assay Description
Inhibitory activity against Lysophosphatidic acid acyltransferase-beta expressed in Sf9 insect cell membranes |
Bioorg Med Chem Lett 14: 2303-8 (2004)
Article DOI: 10.1016/j.bmcl.2004.01.104
BindingDB Entry DOI: 10.7270/Q2Q23ZPH |
More data for this
Ligand-Target Pair | |
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