| Reaction Details |
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 | Report a problem with these data |
| Target | Melanocortin receptor 4 |
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| Ligand | BDBM50174068 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_320947 (CHEMBL882466) |
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| Ki | 157±n/a nM |
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| Citation |  Fisher, MJ; Backer, RT; Collado, I; de Frutos, O; Husain, S; Hsiung, HM; Kuklish, SL; Mateo, AI; Mullaney, JT; Ornstein, PL; Paredes, CG; O'Brian, TP; Richardson, TI; Shah, J; Zgombick, JM; Briner, K Privileged structure based ligands for melanocortin receptors--substituted benzylic piperazine derivatives. Bioorg Med Chem Lett15:4973-8 (2005) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Melanocortin receptor 4 |
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| Name: | Melanocortin receptor 4 |
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| Synonyms: | MC4-R | MC4R | MC4R_HUMAN | Melanocortin MC4 | Melanocortin receptor 4 (MC-4) | Melanocortin receptor 4 (MC4-R) | Melanocortin receptor 4 (MC4R) |
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| Type: | Enzyme |
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| Mol. Mass.: | 36949.50 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P32245 |
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| Residue: | 332 |
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| Sequence: | MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLL
ENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVN
IDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVS
GILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGAN
MKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPL
IYALRSQELRKTFKEIICCYPLGGLCDLSSRY
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| BDBM50174068 |
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| n/a |
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| Name | BDBM50174068 |
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| Synonyms: | CHEMBL198607 | N-Ethyl-N-[2-(2-fluoro-phenyl)-2-(4-methyl-piperazin-1-yl)-ethyl]-methanesulfonamide |
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| Type | Small organic molecule |
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| Emp. Form. | C16H26FN3O2S |
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| Mol. Mass. | 343.46 |
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| SMILES | CCN(CC(N1CCN(C)CC1)c1ccccc1F)S(C)(=O)=O |
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| Structure | 
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