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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Melanocortin receptor 4 | ||
| Ligand | BDBM50174877 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_326975 (CHEMBL868738) | ||
| EC50 | 220±n/a nM | ||
| Citation |  Cheung, AW; Qi, L; Gore, V; Chu, XJ; Bartkovitz, D; Kurylko, G; Swistok, J; Danho, W; Chen, L; Yagaloff, K Preparation of human Melanocortin-4 receptor agonist libraries: linear peptides X-Y-DPhe7-Arg8-Trp(or 2-Nal)9-Z-NH2. Bioorg Med Chem Lett15:5504-8 (2005) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Melanocortin receptor 4 | |||
| Name: | Melanocortin receptor 4 | ||
| Synonyms: | MC4-R | MC4R | MC4R_HUMAN | Melanocortin MC4 | Melanocortin receptor 4 (MC-4) | Melanocortin receptor 4 (MC4-R) | Melanocortin receptor 4 (MC4R) | ||
| Type: | Enzyme | ||
| Mol. Mass.: | 36949.50 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P32245 | ||
| Residue: | 332 | ||
| Sequence: |
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| BDBM50174877 | |||
| n/a | |||
| Name | BDBM50174877 | ||
| Synonyms: | Bu-Apc-DPhe-Arg-2-Nal-Z3-NH2 | CHEMBL369915 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C48H61N9O6 | ||
| Mol. Mass. | 860.0546 | ||
| SMILES | CCCC(=O)N[C@@]1(CC[C@@H](CC1)c1ccccc1)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)NC(Cc1ccc2ccccc2c1)C(=O)N[C@@H](C)C(N)=O |wU:21.22,32.34,9.12,6.5,58.63,wD:6.19,(-4.88,-3.48,;-3.55,-2.71,;-2.22,-3.49,;-.89,-2.71,;-.89,-1.18,;.46,-3.49,;1.8,-2.72,;3.12,-1.96,;3.13,-.43,;1.81,.35,;.47,-.42,;.47,-1.96,;1.82,1.87,;3.15,2.64,;3.15,4.18,;1.82,4.95,;.49,4.18,;.49,2.64,;3.13,-3.49,;3.13,-5.03,;4.46,-2.71,;5.8,-3.49,;5.8,-5.03,;7.13,-5.81,;7.12,-7.35,;8.46,-8.11,;9.8,-7.35,;9.8,-5.8,;8.46,-5.03,;7.13,-2.71,;7.13,-1.18,;8.47,-3.49,;9.8,-2.71,;9.8,-1.18,;11.14,-.4,;11.14,1.14,;12.48,1.91,;12.48,3.46,;13.82,4.23,;11.14,4.23,;11.14,-3.49,;11.14,-5.03,;12.48,-2.71,;13.82,-3.49,;13.82,-5.03,;15.15,-5.81,;16.48,-5.03,;17.82,-5.81,;17.82,-7.35,;19.15,-8.13,;19.15,-9.67,;17.8,-10.44,;16.47,-9.67,;16.48,-8.12,;15.14,-7.35,;15.15,-2.71,;15.15,-1.18,;16.49,-3.49,;17.82,-2.72,;17.81,-1.18,;19.15,-3.47,;20.48,-2.71,;19.15,-5.02,)| | ||
| Structure | 
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