| Reaction Details |
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 | Report a problem with these data |
| Target | Nuclear receptor subfamily 4 group A member 2 |
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| Ligand | BDBM50577613 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2227573 (CHEMBL5141086) |
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| IC50 | 3800±n/a nM |
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| Citation |  Willems, S; Merk, D Medicinal Chemistry and Chemical Biology of Nurr1 Modulators: An Emerging Strategy in Neurodegeneration. J Med Chem65:9548-9563 (2022) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Nuclear receptor subfamily 4 group A member 2 |
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| Name: | Nuclear receptor subfamily 4 group A member 2 |
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| Synonyms: | NOT | NR4A2 | NR4A2_HUMAN | NURR1 | TINUR |
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| Type: | PROTEIN |
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| Mol. Mass.: | 66603.77 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_453027 |
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| Residue: | 598 |
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| Sequence: | MPCVQAQYGSSPQGASPASQSYSYHSSGEYSSDFLTPEFVKFSMDLTNTEITATTSLPSF
STFMDNYSTGYDVKPPCLYQMPLSGQQSSIKVEDIQMHNYQQHSHLPPQSEEMMPHSGSV
YYKPSSPPTPTTPGFQVQHSPMWDDPGSLHNFHQNYVATTHMIEQRKTPVSRLSLFSFKQ
SPPGTPVSSCQMRFDGPLHVPMNPEPAGSHHVVDGQTFAVPNPIRKPASMGFPGLQIGHA
SQLLDTQVPSPPSRGSPSNEGLCAVCGDNAACQHYGVRTCEGCKGFFKRTVQKNAKYVCL
ANKNCPVDKRRRNRCQYCRFQKCLAVGMVKEVVRTDSLKGRRGRLPSKPKSPQEPSPPSP
PVSLISALVRAHVDSNPAMTSLDYSRFQANPDYQMSGDDTQHIQQFYDLLTGSMEIIRGW
AEKIPGFADLPKADQDLLFESAFLELFVLRLAYRSNPVEGKLIFCNGVVLHRLQCVRGFG
EWIDSIVEFSSNLQNMNIDISAFSCIAALAMVTERHGLKEPKRVEELQNKIVNCLKDHVT
FNNGGLNRPNYLSKLLGKLPELRTLCTQGLQRIFYLKLEDLVPPPAIIDKLFLDTLPF
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| BDBM50577613 |
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| n/a |
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| Name | BDBM50577613 |
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| Synonyms: | CHEMBL4857804 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H14N2O2 |
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| Mol. Mass. | 266.2946 |
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| SMILES | COC(=O)c1cn(C)c2ccc(cc12)-c1cccnc1 |
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| Structure | 
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