| Reaction Details |
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 | Report a problem with these data |
| Target | Lysine-specific demethylase 4D |
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| Ligand | BDBM50153318 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2227627 (CHEMBL5141140) |
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| IC50 | 79±n/a nM |
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| Citation |  Wu, Q; Young, B; Wang, Y; Davidoff, AM; Rankovic, Z; Yang, J Recent Advances with KDM4 Inhibitors and Potential Applications. J Med Chem65:9564-9579 (2022) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Lysine-specific demethylase 4D |
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| Name: | Lysine-specific demethylase 4D |
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| Synonyms: | JHDM3D | JHDM3D | JMJD2D | JmjC domain-containing histone demethylation protein 3D | Jumonji domain-containing protein 2D | KDM4D | KDM4D_HUMAN | Lysine-specific demethylase 4D |
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| Type: | PROTEIN |
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| Mol. Mass.: | 58627.79 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_102441 |
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| Residue: | 523 |
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| Sequence: | METMKSKANCAQNPNCNIMIFHPTKEEFNDFDKYIAYMESQGAHRAGLAKIIPPKEWKAR
ETYDNISEILIATPLQQVASGRAGVFTQYHKKKKAMTVGEYRHLANSKKYQTPPHQNFED
LERKYWKNRIYNSPIYGADISGSLFDENTKQWNLGHLGTIQDLLEKECGVVIEGVNTPYL
YFGMWKTTFAWHTEDMDLYSINYLHLGEPKTWYVVPPEHGQRLERLARELFPGSSRGCGA
FLRHKVALISPTVLKENGIPFNRITQEAGEFMVTFPYGYHAGFNHGFNCAEAINFATPRW
IDYGKMASQCSCGEARVTFSMDAFVRILQPERYDLWKRGQDRAVVDHMEPRVPASQELST
QKEVQLPRRAALGLRQLPSHWARHSPWPMAARSGTRCHTLVCSSLPRRSAVSGTATQPRA
AAVHSSKKPSSTPSSTPGPSAQIIHPSNGRRGRGRPPQKLRAQELTLQTPAKRPLLAGTT
CTASGPEPEPLPEDGALMDKPVPLSPGLQHPVKASGCSWAPVP
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| BDBM50153318 |
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| n/a |
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| Name | BDBM50153318 |
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| Synonyms: | CHEMBL3775237 |
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| Type | Small organic molecule |
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| Emp. Form. | C11H10N2O3 |
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| Mol. Mass. | 218.2087 |
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| SMILES | OC(=O)c1ccncc1NCc1ccco1 |
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| Structure | 
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