| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Histamine H3 receptor |
|---|
| Ligand | BDBM22542 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_327753 (CHEMBL861794) |
|---|
| Ki | 0.4±n/a nM |
|---|
| Citation |  Vaccaro, WD; Sher, R; Berlin, M; Shih, NY; Aslanian, R; Schwerdt, JH; McCormick, KD; Piwinski, JJ; West, RE; Anthes, JC; Williams, SM; Wu, RL; She, HS; Rivelli, MA; Mutter, JC; Corboz, MR; Hey, JA; Favreau, L Novel histamine H3 receptor antagonists based on the 4-[(1H-imidazol-4-yl)methyl]piperidine scaffold. Bioorg Med Chem Lett16:395-9 (2005) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Histamine H3 receptor |
|---|
| Name: | Histamine H3 receptor |
|---|
| Synonyms: | HISTAMINE H3 | HRH3 | HRH3_CAVPO | Histamine H3 receptor |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 48753.61 |
|---|
| Organism: | GUINEA PIG |
|---|
| Description: | HISTAMINE H3 HRH3 GUINEA PIG::Q9JI35 |
|---|
| Residue: | 445 |
|---|
| Sequence: | MERAPPDGLMNASGALAGEAAAAAGGARTFSAAWTAVLAALMALLIVATVLGNALVMLAF
VADSSLRTQNNFFLLNLAISDFLVGVFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCT
SSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMVLVWVLAFLLYGPAILSWEYLSG
GSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGARE
AGPDPLPEAQSSPPQPPPGCWGCWPKGQGESMPLHRYGVGEAGPGAEAGEAALGGGSGAA
ASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSL
AIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFR
RAFTKLLCPQKLKVQPHSSLEHCWK
|
|
|
|---|
| BDBM22542 |
|---|
| n/a |
|---|
| Name | BDBM22542 |
|---|
| Synonyms: | 4-(1H-imidazol-4-ylmethyl)piperidine | 4-(1H-imidazol-5-ylmethyl)piperidine | Immepip |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C9H15N3 |
|---|
| Mol. Mass. | 165.2355 |
|---|
| SMILES | C(C1CCNCC1)c1cnc[nH]1 |
|---|
| Structure | 
|
|---|
Search and Browse
