| Reaction Details |
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 | Report a problem with these data |
| Target | Carbonic anhydrase 7 |
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| Ligand | BDBM50569706 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2230680 (CHEMBL5144452) |
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| Ki | 8.7±n/a nM |
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| Citation |  Akgül, Ö; Lucarini, E; Mannelli, LDC; Ghelardini, C; D'Ambrosio, K; Buonanno, M; Monti, SM; De Simone, G; Angeli, A; Supuran, CT; Carta, F Sultam based Carbonic Anhydrase VII inhibitors for the management of neuropathic pain. Eur J Med Chem227:0 (2022) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Carbonic anhydrase 7 |
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| Name: | Carbonic anhydrase 7 |
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| Synonyms: | CA-VII | CA7 | CAH7_HUMAN | Carbonate dehydratase VII | Carbonic anhydrase | Carbonic anhydrase VII | Carbonic anhydrase VII (CA VII) |
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| Type: | Enzyme |
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| Mol. Mass.: | 29664.11 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Human cloned isozyme. |
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| Residue: | 264 |
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| Sequence: | MTGHHGWGYGQDDGPSHWHKLYPIAQGDRQSPINIISSQAVYSPSLQPLELSYEACMSLS
ITNNGHSVQVDFNDSDDRTVVTGGPLEGPYRLKQFHFHWGKKHDVGSEHTVDGKSFPSEL
HLVHWNAKKYSTFGEAASAPDGLAVVGVFLETGDEHPSMNRLTDALYMVRFKGTKAQFSC
FNPKCLLPASRHYWTYPGSLTTPPLSESVTWIVLREPICISERQMGKFRSLLFTSEDDER
IHMVNNFRPPQPLKGRVVKASFRA
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| BDBM50569706 |
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| n/a |
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| Name | BDBM50569706 |
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| Synonyms: | CHEMBL4872649 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H19N3O4S2 |
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| Mol. Mass. | 381.47 |
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| SMILES | NS(=O)(=O)c1ccc(cc1)N1CN(Cc2ccccc2)CCS1(=O)=O |
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| Structure | 
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