| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine kinase |
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| Ligand | BDBM50178018 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_325687 (CHEMBL864546) |
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| IC50 | 0.9±n/a nM |
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| Citation |  Bookser, BC; Ugarkar, BG; Matelich, MC; Lemus, RH; Allan, M; Tsuchiya, M; Nakane, M; Nagahisa, A; Wiesner, JB; Erion, MD Adenosine kinase inhibitors. 6. Synthesis, water solubility, and antinociceptive activity of 5-phenyl-7-(5-deoxy-beta-D-ribofuranosyl)pyrrolo[2,3-d]pyrimidines substituted at C4 with glycinamides and related compounds. J Med Chem48:7808-20 (2005) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine kinase |
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| Name: | Adenosine kinase |
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| Synonyms: | ADK | ADK_HUMAN |
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| Type: | PROTEIN |
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| Mol. Mass.: | 40545.97 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1467841 |
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| Residue: | 362 |
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| Sequence: | MAAAEEEPKPKKLKVEAPQALRENILFGMGNPLLDISAVVDKDFLDKYSLKPNDQILAED
KHKELFDELVKKFKVEYHAGGSTQNSIKVAQWMIQQPHKAATFFGCIGIDKFGEILKRKA
AEAHVDAHYYEQNEQPTGTCAACITGDNRSLIANLAAANCYKKEKHLDLEKNWMLVEKAR
VCYIAGFFLTVSPESVLKVAHHASENNRIFTLNLSAPFISQFYKESLMKVMPYVDILFGN
ETEAATFAREQGFETKDIKEIAKKTQALPKMNSKRQRIVIFTQGRDDTIMATESEVTAFA
VLDQDQKEIIDTNGAGDAFVGGFLSQLVSDKPLTECIRAGHYAASIIIRRTGCTFPEKPD
FH
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| BDBM50178018 |
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| n/a |
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| Name | BDBM50178018 |
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| Synonyms: | 2-(3-phenyl-1-(beta-D-ribofuranosyl)-pyrazolo[3,4-d]pyrimidin-4-ylamino)-N-phenylacetamide | CHEMBL198566 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H24N6O5 |
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| Mol. Mass. | 476.4846 |
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| SMILES | OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1nc(-c2ccccc2)c2c(NCC(=O)Nc3ccccc3)ncnc12 |
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| Structure | 
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