| Reaction Details |
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 | Report a problem with these data |
| Target | Retinoic acid receptor RXR-beta |
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| Ligand | BDBM50179118 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_349698 (CHEMBL866289) |
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| EC50 | 161±n/a nM |
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| Citation |  Farmer, LJ; Marron, KS; Canan Koch, SS; Hwang, CK; Kallel, EA; Zhi, L; Nadzan, AM; Robertson, DW; Bennani, YL Aza-retinoids as novel retinoid X receptor-specific agonists. Bioorg Med Chem Lett16:2352-6 (2006) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Retinoic acid receptor RXR-beta |
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| Name: | Retinoic acid receptor RXR-beta |
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| Synonyms: | NR2B2 | Nuclear receptor subfamily 2 group B member 2 | RXRB | RXRB_HUMAN | Retinoic acid receptor RXR-beta | Retinoid X receptor beta | Retinoid receptor |
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| Type: | PROTEIN |
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| Mol. Mass.: | 56932.89 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_39045 |
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| Residue: | 533 |
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| Sequence: | MSWAARPPFLPQRHAAGQCGPVGVRKEMHCGVASRWRRRRPWLDPAAAAAAAVAGGEQQT
PEPEPGEAGRDGMGDSGRDSRSPDSSSPNPLPQGVPPPSPPGPPLPPSTAPSLGGSGAPP
PPPMPPPPLGSPFPVISSSMGSPGLPPPAPPGFSGPVSSPQINSTVSLPGGGSGPPEDVK
PPVLGVRGLHCPPPPGGPGAGKRLCAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLTYS
CRDNKDCTVDKRQRNRCQYCRYQKCLATGMKREAVQEERQRGKDKDGDGEGAGGAPEEMP
VDRILEAELAVEQKSDQGVEGPGGTGGSGSSPNDPVTNICQAADKQLFTLVEWAKRIPHF
SSLPLDDQVILLRAGWNELLIASFSHRSIDVRDGILLATGLHVHRNSAHSAGVGAIFDRV
LTELVSKMRDMRMDKTELGCLRAIILFNPDAKGLSNPSEVEVLREKVYASLETYCKQKYP
EQQGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQLA
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| BDBM50179118 |
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| n/a |
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| Name | BDBM50179118 |
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| Synonyms: | (S,2E,4E)-3-methyl-5-(1-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)pyrrolidin-2-yl)penta-2,4-dienoic acid | CHEMBL378926 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H33NO2 |
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| Mol. Mass. | 367.5243 |
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| SMILES | C\C(\C=C\[C@@H]1CCCN1c1ccc2c(c1)C(C)(C)CCC2(C)C)=C/C(O)=O |
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| Structure | 
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