| Reaction Details |
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 | Report a problem with these data |
| Target | Interstitial collagenase |
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| Ligand | BDBM50180016 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_329819 (CHEMBL862782) |
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| IC50 | >1000±n/a nM |
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| Citation |  Pirard, B; Matter, H Matrix metalloproteinase target family landscape: a chemometrical approach to ligand selectivity based on protein binding site analysis. J Med Chem49:51-69 (2006) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Interstitial collagenase |
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| Name: | Interstitial collagenase |
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| Synonyms: | CLG | Fibroblast collagenase | MMP1 | MMP1_HUMAN | Matrix metalloproteinase-1 | Matrix metalloproteinase-1 (MMP-1) |
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| Type: | Enzyme |
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| Mol. Mass.: | 54010.26 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P03956 |
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| Residue: | 469 |
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| Sequence: | MHSFPPLLLLLFWGVVSHSFPATLETQEQDVDLVQKYLEKYYNLKNDGRQVEKRRNSGPV
VEKLKQMQEFFGLKVTGKPDAETLKVMKQPRCGVPDVAQFVLTEGNPRWEQTHLTYRIEN
YTPDLPRADVDHAIEKAFQLWSNVTPLTFTKVSEGQADIMISFVRGDHRDNSPFDGPGGN
LAHAFQPGPGIGGDAHFDEDERWTNNFREYNLHRVAAHELGHSLGLSHSTDIGALMYPSY
TFSGDVQLAQDDIDGIQAIYGRSQNPVQPIGPQTPKACDSKLTFDAITTIRGEVMFFKDR
FYMRTNPFYPEVELNFISVFWPQLPNGLEAAYEFADRDEVRFFKGNKYWAVQGQNVLHGY
PKDIYSSFGFPRTVKHIDAALSEENTGKTYFFVANKYWRYDEYKRSMDPGYPKMIAHDFP
GIGHKVDAVFMKDGFFYFFHGTRQYKFDPKTKRILTLQKANSWFNCRKN
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| BDBM50180016 |
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| n/a |
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| Name | BDBM50180016 |
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| Synonyms: | (S)-2-((4-(4-bromobenzamido)phenylsulfonyl)methyl)-3-(1H-indol-3-yl)propanoic acid | CHEMBL199917 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H21BrN2O5S |
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| Mol. Mass. | 541.414 |
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| SMILES | OC(=O)[C@H](Cc1c[nH]c2ccccc12)CS(=O)(=O)c1ccc(NC(=O)c2ccc(Br)cc2)cc1 |
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| Structure | 
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