| Reaction Details |
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 | Report a problem with these data |
| Target | Serine/threonine-protein kinase PknG |
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| Ligand | BDBM50600797 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2234891 (CHEMBL5148663) |
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| Kd | 2000±n/a nM |
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| Citation |  Burastero, O; Defelipe, LA; Gola, G; Tateosian, NL; Lopez, ED; Martinena, CB; Arcon, JP; Traian, MD; Wetzler, DE; Bento, I; Barril, X; Ramirez, J; Marti, MA; Garcia-Alai, MM; Turjanski, AG Cosolvent Sites-Based Discovery of J Med Chem65:9691-9705 (2022) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Serine/threonine-protein kinase PknG |
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| Name: | Serine/threonine-protein kinase PknG |
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| Synonyms: | 2.7.11.1 | PKNG_MYCTU | pknG |
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| Type: | PROTEIN |
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| Mol. Mass.: | 81567.31 |
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| Organism: | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) |
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| Description: | ChEMBL_102879 |
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| Residue: | 750 |
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| Sequence: | MAKASETERSGPGTQPADAQTATSATVRPLSTQAVFRPDFGDEDNFPHPTLGPDTEPQDR
MATTSRVRPPVRRLGGGLVEIPRAPDIDPLEALMTNPVVPESKRFCWNCGRPVGRSDSET
KGASEGWCPYCGSPYSFLPQLNPGDIVAGQYEVKGCIAHGGLGWIYLALDRNVNGRPVVL
KGLVHSGDAEAQAMAMAERQFLAEVVHPSIVQIFNFVEHTDRHGDPVGYIVMEYVGGQSL
KRSKGQKLPVAEAIAYLLEILPALSYLHSIGLVYNDLKPENIMLTEEQLKLIDLGAVSRI
NSFGYLYGTPGFQAPEIVRTGPTVATDIYTVGRTLAALTLDLPTRNGRYVDGLPEDDPVL
KTYDSYGRLLRRAIDPDPRQRFTTAEEMSAQLTGVLREVVAQDTGVPRPGLSTIFSPSRS
TFGVDLLVAHTDVYLDGQVHAEKLTANEIVTALSVPLVDPTDVAASVLQATVLSQPVQTL
DSLRAARHGALDADGVDFSESVELPLMEVRALLDLGDVAKATRKLDDLAERVGWRWRLVW
YRAVAELLTGDYDSATKHFTEVLDTFPGELAPKLALAATAELAGNTDEHKFYQTVWSTND
GVISAAFGLARARSAEGDRVGAVRTLDEVPPTSRHFTTARLTSAVTLLSGRSTSEVTEEQ
IRDAARRVEALPPTEPRVLQIRALVLGGALDWLKDNKASTNHILGFPFTSHGLRLGVEAS
LRSLARVAPTQRHRYTLVDMANKVRPTSTF
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| BDBM50600797 |
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| n/a |
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| Name | BDBM50600797 |
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| Synonyms: | CHEMBL5183885 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H12FN3O2 |
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| Mol. Mass. | 297.2838 |
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| SMILES | NC(=O)c1c(N)c(C(=O)c2ccc(F)cc2)n2ccccc12 |
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| Structure | 
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