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TargetD(2) dopamine receptor
LigandBDBM50116766
Substrate/Competitorn/a
Meas. Tech.ChEMBL_2237568 (CHEMBL5151464)
Kd 0.014900±n/a nM
Citation Tropmann, K; Bresinsky, M; Forster, L; Mönnich, D; Buschauer, A; Wittmann, HJ; Hübner, H; Gmeiner, P; Pockes, S; Strasser, A Abolishing Dopamine D J Med Chem64:8684-8709 (2021) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
D(2) dopamine receptor
Name:D(2) dopamine receptor
Synonyms:D(2) dopamine receptor | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2 | DRD2_HUMAN | Dopamine D2 receptor | Dopamine D2 receptor (D2) | Dopamine D2 receptor (D2R) | Dopamine D2A | Dopamine2-like | d2
Type:Cell-surface receptors
Mol. Mass.:50647.10
Organism:Homo sapiens (Human)
Description:P14416
Residue:443
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVS
REKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTA
SILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQN
ECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPL
KGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPP
SHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSR
RKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSA
VNPIIYTTFNIEFRKAFLKILHC
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  Blast E-value cutoff:
BDBM50116766
n/a
NameBDBM50116766
Synonyms:(-)-Pramipexole | (6S)-N(6)-propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine | 2,6-Benzothiazolediamine, 4,5,6,7-tetrahydro-N(sup 6)-propyl-, (S)- | CHEMBL301265 | PRAMIPEXOLE | cid_119570
TypeSmall organic molecule
Emp. Form.C10H17N3S
Mol. Mass.211.327
SMILESCCCN[C@H]1CCc2nc(N)sc2C1 |r|
Structure
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