| Reaction Details |
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 | Report a problem with these data |
| Target | C-C chemokine receptor type 4 |
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| Ligand | BDBM50183102 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_350559 (CHEMBL870148) |
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| IC50 | 37±n/a nM |
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| Citation |  Wang, X; Xu, F; Xu, Q; Mahmud, H; Houze, J; Zhu, L; Akerman, M; Tonn, G; Tang, L; McMaster, BE; Dairaghi, DJ; Schall, TJ; Collins, TL; Medina, JC Optimization of 2-aminothiazole derivatives as CCR4 antagonists. Bioorg Med Chem Lett16:2800-3 (2006) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| C-C chemokine receptor type 4 |
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| Name: | C-C chemokine receptor type 4 |
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| Synonyms: | C-C CKR-4 | C-C chemokine receptor type 4 | C-C chemokine receptor type 4 (CCR4) | CC-CKR-4 | CCR-4 | CCR4 | CCR4_HUMAN | CD_antigen=CD194 | CMKBR4 | K5-5 |
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| Type: | Enzyme |
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| Mol. Mass.: | 41406.41 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P51679 |
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| Residue: | 360 |
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| Sequence: | MNPTDIADTTLDESIYSNYYLYESIPKPCTKEGIKAFGELFLPPLYSLVFVFGLLGNSVV
VLVLFKYKRLRSMTDVYLLNLAISDLLFVFSLPFWGYYAADQWVFGLGLCKMISWMYLVG
FYSGIFFVMLMSIDRYLAIVHAVFSLRARTLTYGVITSLATWSVAVFASLPGFLFSTCYT
ERNHTYCKTKYSLNSTTWKVLSSLEINILGLVIPLGIMLFCYSMIIRTLQHCKNEKKNKA
VKMIFAVVVLFLGFWTPYNIVLFLETLVELEVLQDCTFERYLDYAIQATETLAFVHCCLN
PIIYFFLGEKFRKYILQLFKTCRGLFVLCQYCGLLQIYSADTPSSSYTQSTMDHDLHDAL
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| BDBM50183102 |
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| n/a |
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| Name | BDBM50183102 |
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| Synonyms: | CHEMBL205279 | N-(4-tert-butylthiazol-2-yl)-1-methyl-1H-indol-4-amine |
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| Type | Small organic molecule |
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| Emp. Form. | C16H19N3S |
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| Mol. Mass. | 285.407 |
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| SMILES | Cn1ccc2c(Nc3nc(cs3)C(C)(C)C)cccc12 |
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| Structure | 
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