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TargetProstanoid DP receptor
LigandBDBM50184244
Substrate/Competitorn/a
Meas. Tech.ChEMBL_364757
Ki 2.6±n/a nM
Citation Sturino CFLachance NBoyd MBerthelette CLabelle MLi LRoy BScheigetz JTsou NBrideau CCauchon ECarriere MCDenis DGreig GKargman SLamontagne SMathieu MCSawyer NSlipetz DO'Neill GWang ZZamboni RMetters KMYoung RN Identification of an indole series of prostaglandin D2 receptor antagonists. Bioorg Med Chem Lett 16:3043-8 (2006) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Prostanoid DP receptor
Name:Prostanoid DP receptor
Synonyms:Prostaglandin D2 | Prostaglandin D2 receptor
Type:Enzyme
Mol. Mass.:40288.87
Organism:Homo sapiens (Human)
Description:Q13258
Residue:359
Sequence:
MKSPFYRCQNTTSVEKGNSAVMGGVLFSTGLLGNLLALGLLARSGLGWCSRRPLRPLPSV
FYMLVCGLTVTDLLGKCLLSPVVLAAYAQNRSLRVLAPALDNSLCQAFAFFMSFFGLSST
LQLLAMALECWLSLGHPFFYRRHITLRLGALVAPVVSAFSLAFCALPFMGFGKFVQYCPG
TWCFIQMVHEEGSLSVLGYSVLYSSLMALLVLATVLCNLGAMRNLYAMHRRLQRHPRSCT
RDCAEPRADGREASPQPLEELDHLLLLALMTVLFTMCSLPVIYRAYYGAFKDVKEKNRTS
EEAEDLRALRFLSVISIVDPWIFIIFRSPVFRIFFHKIFIRPLRYRSRCSNSTNMESSL
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50184244
n/a
NameBDBM50184244
Synonyms:2-(9-(4-chlorobenzyl)-8-bromo-2,3,4,9-tetrahydro-1H-carbazol-1-yl)acetic acid | CHEMBL378125
TypeSmall organic molecule
Emp. Form.C21H19BrClNO2
Mol. Mass.432.738
SMILESOC(=O)CC1CCCc2c1n(Cc1ccc(Cl)cc1)c1c(Br)cccc21
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: