| Reaction Details |
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 | Report a problem with these data |
| Target | Cannabinoid receptor 1 |
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| Ligand | BDBM50603279 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2243596 (CHEMBL5157806) |
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| Ki | 0.570000±n/a nM |
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| Citation |  Papanastasiou, IP; Georgiadis, MO; Iliopoulos-Tsoutsouvas, C; Paronis, CA; Brust, CA; Tran, NK; Ji, L; Ma, X; Wood, JT; Zvonok, N; Tong, F; Bohn, LM; Nikas, SP; Makriyannis, A Improved cyclobutyl nabilone analogs as potent CB1 receptor agonists. Eur J Med Chem230:0 (2022) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cannabinoid receptor 1 |
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| Name: | Cannabinoid receptor 1 |
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| Synonyms: | Brain-type cannabinoid receptor | CANNABINOID CB1 | CB-R | CB1 | CNR1_RAT | Cannabinoid CB1 receptor | Cannabinoid receptor | Cannabinoid receptor 1 (CB1) | Cnr1 | Skr6 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 52856.55 |
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| Organism: | Rattus norvegicus (rat) |
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| Description: | P20272 |
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| Residue: | 473 |
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| Sequence: | MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQE
KMTAGDNSPLVPAGDTTNITEFYNKSLSSFKENEENIQCGENFMDMECFMILNPSQQLAI
AVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFVDFHV
FHRKDSPNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCL
MWTIAIVIAVLPLLGWNCKKLQSVCSDIFPLIDETYLMFWIGVTSVLLLFIVYAYMYILW
KAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPL
LAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTA
QPLDNSMGDSDCLHKHANNTASMHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
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| BDBM50603279 |
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| n/a |
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| Name | BDBM50603279 |
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| Synonyms: | CHEMBL5203974 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H33N3O3 |
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| Mol. Mass. | 399.5264 |
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| SMILES | [H][C@@]12C[C@H](O)CC[C@@]1([H])C(C)(C)Oc1cc(cc(O)c21)C1(CCCCN=[N+]=[N-])CCC1 |r| |
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| Structure | 
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