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TargetDNA polymerase beta
LigandBDBM50184754
Substrate/Competitorn/a
Meas. Tech.ChEMBL_356788
IC50 8800±n/a nM
Citation Doncaster JREtchells LLKershaw NMNakamura RRyan HTakeuchi RSakaguchi KSardarian AWhitehead RC Synthetic analogues of the manzamenones and plakoridines which inhibit DNA polymerase. Bioorg Med Chem Lett 16:2877-81 (2006) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
DNA polymerase beta
Name:DNA polymerase beta
Synonyms:DNA polymerase beta (Pol β)
Type:Protein
Mol. Mass.:38188.76
Organism:Homo sapiens (Human)
Description:n/a
Residue:335
Sequence:
MSKRKAPQETLNGGITDMLTELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAK
KLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVDEGIK
TLEDLRKNEDKLNHHQRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVCGS
FRRGAESSGDMDVLLTHPSFTSESTKQPKLLHQVVEQLQKVHFITDTLSKGETKFMGVCQ
LPSKNDEKEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRP
LGVTGVAGEPLPVDSEKDIFDYIQWKYREPKDRSE
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  Blast E-value cutoff:
BDBM50184754
n/a
NameBDBM50184754
Synonyms:(E)-methyl-3,6-dioxo-4-docosenoate | CHEMBL425779
TypeSmall organic molecule
Emp. Form.C23H40O4
Mol. Mass.380.5613
SMILESCCCCCCCCCCCCCCCCC(=O)C=CC(=O)CC(=O)OC |w:18.17|
Structure
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