| Reaction Details |
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 | Report a problem with these data |
| Target | Aryl hydrocarbon receptor |
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| Ligand | BDBM50603554 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2244281 (CHEMBL5158491) |
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| EC50 | 0.830000±n/a nM |
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| Citation |  Tian, C; Zhang, G; Xia, Z; Chen, N; Yang, S; Li, L Identification of triazolopyridine derivatives as a new class of AhR agonists and evaluation of anti-psoriasis effect in a mouse model. Eur J Med Chem231:0 (2022) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Aryl hydrocarbon receptor |
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| Name: | Aryl hydrocarbon receptor |
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| Synonyms: | AHR | AHR_HUMAN | BHLHE76 | Class E basic helix-loop-helix protein 76 | aryl hydrocarbon receptor precursor |
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| Type: | PROTEIN |
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| Mol. Mass.: | 96143.77 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1503828 |
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| Residue: | 848 |
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| Sequence: | MNSSSANITYASRKRRKPVQKTVKPIPAEGIKSNPSKRHRDRLNTELDRLASLLPFPQDV
INKLDKLSVLRLSVSYLRAKSFFDVALKSSPTERNGGQDNCRAANFREGLNLQEGEFLLQ
ALNGFVLVVTTDALVFYASSTIQDYLGFQQSDVIHQSVYELIHTEDRAEFQRQLHWALNP
SQCTESGQGIEEATGLPQTVVCYNPDQIPPENSPLMERCFICRLRCLLDNSSGFLAMNFQ
GKLKYLHGQKKKGKDGSILPPQLALFAIATPLQPPSILEIRTKNFIFRTKHKLDFTPIGC
DAKGRIVLGYTEAELCTRGSGYQFIHAADMLYCAESHIRMIKTGESGMIVFRLLTKNNRW
TWVQSNARLLYKNGRPDYIIVTQRPLTDEEGTEHLRKRNTKLPFMFTTGEAVLYEATNPF
PAIMDPLPLRTKNGTSGKDSATTSTLSKDSLNPSSLLAAMMQQDESIYLYPASSTSSTAP
FENNFFNESMNECRNWQDNTAPMGNDTILKHEQIDQPQDVNSFAGGHPGLFQDSKNSDLY
SIMKNLGIDFEDIRHMQNEKFFRNDFSGEVDFRDIDLTDEILTYVQDSLSKSPFIPSDYQ
QQQSLALNSSCMVQEHLHLEQQQQHHQKQVVVEPQQQLCQKMKHMQVNGMFENWNSNQFV
PFNCPQQDPQQYNVFTDLHGISQEFPYKSEMDSMPYTQNFISCNQPVLPQHSKCTELDYP
MGSFEPSPYPTTSSLEDFVTCLQLPENQKHGLNPQSAIITPQTCYAGAVSMYQCQPEPQH
THVGQMQYNPVLPGQQAFLNKFQNGVLNETYPAELNNINNTQTTTHLQPLHHPSEARPFP
DLTSSGFL
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| BDBM50603554 |
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| n/a |
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| Name | BDBM50603554 |
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| Synonyms: | CHEMBL5181725 |
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| Type | Small organic molecule |
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| Emp. Form. | C12H7BrClN3 |
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| Mol. Mass. | 308.561 |
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| SMILES | Clc1ccc(cc1)-c1nc2ccc(Br)cn2n1 |
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| Structure | 
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