| Reaction Details |
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 | Report a problem with these data |
| Target | Neuropeptide Y receptor type 2 |
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| Ligand | BDBM50185364 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_344947 |
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| Ki | 890±n/a nM |
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| Citation |  Balasubramaniam, A; Mullins, DE; Lin, S; Zhai, W; Tao, Z; Dhawan, VC; Guzzi, M; Knittel, JJ; Slack, K; Herzog, H; Parker, EM Neuropeptide Y (NPY) Y4 receptor selective agonists based on NPY(32-36): development of an anorectic Y4 receptor selective agonist with picomolar affinity. J Med Chem49:2661-5 (2006) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Neuropeptide Y receptor type 2 |
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| Name: | Neuropeptide Y receptor type 2 |
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| Synonyms: | NPY-Y2 | NPY-Y2 receptor | NPY2-R | NPY2R | NPY2R_HUMAN | Neuropeptide Y receptor type 2 | Y2 receptor | neuropeptide Y receptor Y2 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 42734.65 |
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| Organism: | Homo sapiens (Human) |
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| Description: | NPY-Y2 NPY2R HUMAN::P49146 |
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| Residue: | 381 |
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| Sequence: | MGPIGAEADENQTVEEMKVEQYGPQTTPRGELVPDPEPELIDSTKLIEVQVVLILAYCSI
ILLGVIGNSLVIHVVIKFKSMRTVTNFFIANLAVADLLVNTLCLPFTLTYTLMGEWKMGP
VLCHLVPYAQGLAVQVSTITLTVIALDRHRCIVYHLESKISKRISFLIIGLAWGISALLA
SPLAIFREYSLIEIIPDFEIVACTEKWPGEEKSIYGTVYSLSSLLILYVLPLGIISFSYT
RIWSKLKNHVSPGAANDHYHQRRQKTTKMLVCVVVVFAVSWLPLHAFQLAVDIDSQVLDL
KEYKLIFTVFHIIAMCSTFANPLLYGWMNSNYRKAFLSAFRCEQRLDAIHSEVSVTFKAK
KNLEVRKNSGPNDSFTEATNV
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| BDBM50185364 |
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| n/a |
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| Name | BDBM50185364 |
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| Synonyms: | CHEMBL2371908 | CHEMBL415187 | Sub[-Tyr-Arg-Leu-Arg-Tyr-NH2]2 |
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| Type | Small organic molecule |
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| Emp. Form. | C80H122N24O18 |
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| Mol. Mass. | 1707.9747 |
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| SMILES | [#6]-[#6](-[#6])-[#6]-[#6@H](-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#7]-[#6](=O)-[#6@H](-[#6]-c1ccc(-[#8])cc1)-[#7]-[#6](=O)-[#6@@H](-[#7])-[#6]-[#6]-[#6]-[#6]-[#6@H](-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-c1ccc(-[#8])cc1)-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6](-[#6])-[#6])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-c1ccc(-[#8])cc1)-[#6](-[#8])=O)-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-c1ccc(-[#8])cc1)-[#6](-[#8])=O |
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| Structure | 
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