| Reaction Details |
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 | Report a problem with these data |
| Target | Cytochrome c oxidase subunit 1 |
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| Ligand | BDBM50140321 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2248532 (CHEMBL5162742) |
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| IC50 | 280±n/a nM |
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| Citation |  Ye, H; Lv, T; Min, T; Mao, D; Chen, X; Ding, B; Zhang, C HR1405-01, a Safe intravenous NSAID with superior anti-inflammatory and analgesic activities in preclinical trials. Eur J Med Chem235:0 (2022) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cytochrome c oxidase subunit 1 |
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| Name: | Cytochrome c oxidase subunit 1 |
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| Synonyms: | COI | COX1_HUMAN | COXI | MT-CO1 | MTCO1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 57042.74 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_746069 |
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| Residue: | 513 |
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| Sequence: | MFADRWLFSTNHKDIGTLYLLFGAWAGVLGTALSLLIRAELGQPGNLLGNDHIYNVIVTA
HAFVMIFFMVMPIMIGGFGNWLVPLMIGAPDMAFPRMNNMSFWLLPPSLLLLLASAMVEA
GAGTGWTVYPPLAGNYSHPGASVDLTIFSLHLAGVSSILGAINFITTIINMKPPAMTQYQ
TPLFVWSVLITAVLLLLSLPVLAAGITMLLTDRNLNTTFFDPAGGGDPILYQHLFWFFGH
PEVYILILPGFGMISHIVTYYSGKKEPFGYMGMVWAMMSIGFLGFIVWAHHMFTVGMDVD
TRAYFTSATMIIAIPTGVKVFSWLATLHGSNMKWSAAVLWALGFIFLFTVGGLTGIVLAN
SSLDIVLHDTYYVVAHFHYVLSMGAVFAIMGGFIHWFPLFSGYTLDQTYAKIHFTIMFIG
VNLTFFPQHFLGLSGMPRRYSDYPDAYTTWNILSSVGSFISLTAVMLMIFMIWEAFASKR
KVLMVEEPSMNLEWLYGCPPPYHTFEEPVYMKS
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| BDBM50140321 |
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| n/a |
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| Name | BDBM50140321 |
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| Synonyms: | (S)-2-[4-((1R,2S)-2-Hydroxy-cyclopentylmethyl)-phenyl]-propionic acid | CHEMBL441414 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H20O3 |
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| Mol. Mass. | 248.3175 |
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| SMILES | C[C@H](C(O)=O)c1ccc(C[C@H]2CCC[C@@H]2O)cc1 |
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| Structure | 
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