| Reaction Details |
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 | Report a problem with these data |
| Target | Aryl hydrocarbon receptor |
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| Ligand | BDBM50605062 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2250271 (CHEMBL5164481) |
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| EC50 | 32±n/a nM |
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| Citation |  Grycová, A; Joo, H; Maier, V; Illés, P; Vyhlídalová, B; Poulíková, K; Sládeková, L; Nádvorník, P; Vrzal, R; Zemánková, L; Pe?inková, P; Poruba, M; Zapletalová, I; Ve?e?a, R; Anzenbacher, P; Ehrmann, J; Ondra, P; Jung, JW; Mani, S; Dvo?ák, Z Targeting the Aryl Hydrocarbon Receptor with Microbial Metabolite Mimics Alleviates Experimental Colitis in Mice. J Med Chem65:6859-6868 (2022) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Aryl hydrocarbon receptor |
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| Name: | Aryl hydrocarbon receptor |
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| Synonyms: | AHR | AHR_HUMAN | BHLHE76 | Class E basic helix-loop-helix protein 76 | aryl hydrocarbon receptor precursor |
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| Type: | PROTEIN |
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| Mol. Mass.: | 96143.77 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1503828 |
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| Residue: | 848 |
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| Sequence: | MNSSSANITYASRKRRKPVQKTVKPIPAEGIKSNPSKRHRDRLNTELDRLASLLPFPQDV
INKLDKLSVLRLSVSYLRAKSFFDVALKSSPTERNGGQDNCRAANFREGLNLQEGEFLLQ
ALNGFVLVVTTDALVFYASSTIQDYLGFQQSDVIHQSVYELIHTEDRAEFQRQLHWALNP
SQCTESGQGIEEATGLPQTVVCYNPDQIPPENSPLMERCFICRLRCLLDNSSGFLAMNFQ
GKLKYLHGQKKKGKDGSILPPQLALFAIATPLQPPSILEIRTKNFIFRTKHKLDFTPIGC
DAKGRIVLGYTEAELCTRGSGYQFIHAADMLYCAESHIRMIKTGESGMIVFRLLTKNNRW
TWVQSNARLLYKNGRPDYIIVTQRPLTDEEGTEHLRKRNTKLPFMFTTGEAVLYEATNPF
PAIMDPLPLRTKNGTSGKDSATTSTLSKDSLNPSSLLAAMMQQDESIYLYPASSTSSTAP
FENNFFNESMNECRNWQDNTAPMGNDTILKHEQIDQPQDVNSFAGGHPGLFQDSKNSDLY
SIMKNLGIDFEDIRHMQNEKFFRNDFSGEVDFRDIDLTDEILTYVQDSLSKSPFIPSDYQ
QQQSLALNSSCMVQEHLHLEQQQQHHQKQVVVEPQQQLCQKMKHMQVNGMFENWNSNQFV
PFNCPQQDPQQYNVFTDLHGISQEFPYKSEMDSMPYTQNFISCNQPVLPQHSKCTELDYP
MGSFEPSPYPTTSSLEDFVTCLQLPENQKHGLNPQSAIITPQTCYAGAVSMYQCQPEPQH
THVGQMQYNPVLPGQQAFLNKFQNGVLNETYPAELNNINNTQTTTHLQPLHHPSEARPFP
DLTSSGFL
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| BDBM50605062 |
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| n/a |
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| Name | BDBM50605062 |
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| Synonyms: | CHEMBL5185943 |
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| Type | Small organic molecule |
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| Emp. Form. | C13H12N2O2S |
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| Mol. Mass. | 260.312 |
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| SMILES | OCc1csc(n1)C(O)c1c[nH]c2ccccc12 |
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| Structure | 
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