Reaction Details |
| Report a problem with these data |
Target | Galanin receptor type 3 |
---|
Ligand | BDBM50187923 |
---|
Substrate/Competitor | n/a |
---|
Meas. Tech. | ChEMBL_384498 (CHEMBL866716) |
---|
Ki | 17±n/a nM |
---|
Citation | Konkel, MJ; Packiarajan, M; Chen, H; Topiwala, UP; Jimenez, H; Talisman, IJ; Coate, H; Walker, MW Amino substituted analogs of 1-phenyl-3-phenylimino-2-indolones with potent galanin Gal3 receptor binding affinity and improved solubility. Bioorg Med Chem Lett16:3950-4 (2006) [PubMed] Article |
---|
More Info.: | Get all data from this article, Assay Method |
---|
|
Galanin receptor type 3 |
---|
Name: | Galanin receptor type 3 |
Synonyms: | GALNR3 | GALR3 | GALR3_HUMAN | Galanin R3 | Galanin receptor 3 | Galanin receptor type 3 |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 39599.97 |
Organism: | Homo sapiens (Human) |
Description: | Galanin R3 GALR3 HUMAN::O60755 |
Residue: | 368 |
Sequence: | MADAQNISLDSPGSVGAVAVPVVFALIFLLGTVGNGLVLAVLLQPGPSAWQEPGSTTDLF
ILNLAVADLCFILCCVPFQATIYTLDAWLFGALVCKAVHLLIYLTMYASSFTLAAVSVDR
YLAVRHPLRSRALRTPRNARAAVGLVWLLAALFSAPYLSYYGTVRYGALELCVPAWEDAR
RRALDVATFAAGYLLPVAVVSLAYGRTLRFLWAAVGPAGAAAAEARRRATGRAGRAMLAV
AALYALCWGPHHALILCFWYGRFAFSPATYACRLASHCLAYANSCLNPLVYALASRHFRA
RFRRLWPCGRRRRHRARRALRRVRPASSGPPGCPGDARPSGRLLAGGGQGPEPREGPVHG
GEAARGPE
|
|
|
BDBM50187923 |
---|
n/a |
---|
Name | BDBM50187923 |
Synonyms: | 1,3-dihydro-1-phenyl-3-[[3-(trilfluoromethyl)phenyl]imino]-2H-indol-2-one | 1-(phenyl)-3-{[3-(trifluoromethyl)phenyl]azamethylene}benzo[d]azolidin-2-one | CHEMBL210288 |
Type | Small organic molecule |
Emp. Form. | C21H13F3N2O |
Mol. Mass. | 366.3359 |
SMILES | FC(F)(F)c1cccc(c1)\N=C1\C(=O)N(c2ccccc12)c1ccccc1 |
Structure |
|