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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Fibroblast growth factor receptor 4 | ||
| Ligand | BDBM50606159 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_2253894 (CHEMBL5168104) | ||
| IC50 | 0.700000±n/a nM | ||
| Citation |  Zhang, X; Wang, Y; Ji, J; Si, D; Bao, X; Yu, Z; Zhu, Y; Zhao, L; Li, W; Liu, J Discovery of 1,6-Naphthyridin-2(1 J Med Chem65:7595-7618 (2022) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Fibroblast growth factor receptor 4 | |||
| Name: | Fibroblast growth factor receptor 4 | ||
| Synonyms: | CD_antigen: CD334 FGFR4 | FGFR-4 | FGFR4 | FGFR4_HUMAN | Fibroblast growth factor receptor | Fibroblast growth factor receptor 4 (FGFR4) | JK2 | JTK2 | TKF | ||
| Type: | Protein | ||
| Mol. Mass.: | 87957.45 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P22455 | ||
| Residue: | 802 | ||
| Sequence: |
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| BDBM50606159 | |||
| n/a | |||
| Name | BDBM50606159 | ||
| Synonyms: | CHEMBL5186034 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C26H28Cl2N4O5 | ||
| Mol. Mass. | 547.43 | ||
| SMILES | CCn1c2cc(N[C@@H]3COCC[C@@H]3NC(=O)C=C)ncc2cc(-c2c(Cl)c(OC)cc(OC)c2Cl)c1=O |r,wU:7.6,12.13,(2,5.01,;.67,4.24,;.67,2.7,;-.67,1.93,;-2,2.7,;-3.33,1.93,;-4.67,2.7,;-6,1.93,;-7.33,2.7,;-8.67,1.93,;-8.67,.38,;-7.33,-.39,;-6,.38,;-4.67,-.39,;-4.67,-1.93,;-3.33,-2.7,;-6,-2.7,;-6,-4.24,;-3.33,.38,;-2,-.39,;-.67,.38,;.67,-.39,;2,.38,;3.34,-.39,;4.67,.38,;4.67,1.93,;6,-.39,;7.33,.38,;8.67,-.39,;6,-1.93,;4.67,-2.7,;4.67,-4.24,;6,-5.01,;3.34,-1.93,;2,-2.7,;2,1.93,;3.34,2.7,)| | ||
| Structure | 
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