| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Target of rapamycin complex subunit LST8 |
|---|
| Ligand | BDBM50606711 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_2261181 (CHEMBL5216192) |
|---|
| IC50 | >0.316228±n/a nM |
|---|
| Citation |  Oleksak, P; Nepovimova, E; Chrienova, Z; Musilek, K; Patocka, J; Kuca, K Contemporary mTOR inhibitor scaffolds to diseases breakdown: A patent review (2015-2021). Eur J Med Chem238:0 (2022) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Target of rapamycin complex subunit LST8 |
|---|
| Name: | Target of rapamycin complex subunit LST8 |
|---|
| Synonyms: | G protein beta subunit-like | GBL | Gable | LST8 | LST8_HUMAN | MLST8 | Mammalian lethal with SEC13 protein 8 | Protein GbetaL | TORC subunit LST8 | Target of rapamycin complex subunit LST8 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 35871.25 |
|---|
| Organism: | Homo sapiens |
|---|
| Description: | ChEMBL_118692 |
|---|
| Residue: | 326 |
|---|
| Sequence: | MNTSPGTVGSDPVILATAGYDHTVRFWQAHSGICTRTVQHQDSQVNALEVTPDRSMIAAA
GYQHIRMYDLNSNNPNPIISYDGVNKNIASVGFHEDGRWMYTGGEDCTARIWDLRSRNLQ
CQRIFQVNAPINCVCLHPNQAELIVGDQSGAIHIWDLKTDHNEQLIPEPEVSITSAHIDP
DASYMAAVNSTGNCYVWNLTGGIGDEVTQLIPKTKIPAHTRYALQCRFSPDSTLLATCSA
DQTCKIWRTSNFSLMTELSIKSGNPGESSRGWMWGCAFSGDSQYIVTASSDNLARLWCVE
TGEIKREYGGHQKAVVCLAFNDSVLG
|
|
|
|---|
| BDBM50606711 |
|---|
| n/a |
|---|
| Name | BDBM50606711 |
|---|
| Synonyms: | CHEMBL5220287 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C61H98N2O15 |
|---|
| Mol. Mass. | 1099.4352 |
|---|
| SMILES | [H][C@@]12CC[C@@H](C)[C@@](O)(O1)C(=O)C(=O)N1CCCC[C@H]1C(=O)O[C@@]([H])(CC(=O)[C@H](C)\C=C(C)\[C@@H](O)[C@@H](OC)C(=O)[C@H](C)C[C@H](C)\C=C\C=C\C=C(C)\C(C2)OCCO)[C@H](C)C[C@@H]1CC[C@@H](OCCCN2C[C@H](C)O[C@H](C)C2)[C@@H](C1)OC |r,c:31,50,t:46,48| |
|---|
| Structure | 
|
|---|
Search and Browse
