| Reaction Details |
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 | Report a problem with these data |
| Target | Dual specificity protein phosphatase 23 |
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| Ligand | BDBM50607110 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2262154 (CHEMBL5217165) |
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| IC50 | >100000±n/a nM |
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| Citation |  He, R; Wang, J; Yu, ZH; Moyers, JS; Michael, MD; Durham, TB; Cramer, JW; Qian, Y; Lin, A; Wu, L; Noinaj, N; Barrett, DG; Zhang, ZY Structure-Based Design of Active-Site-Directed, Highly Potent, Selective, and Orally Bioavailable Low-Molecular-Weight Protein Tyrosine Phosphatase Inhibitors. J Med Chem65:13892-13909 (2022) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Dual specificity protein phosphatase 23 |
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| Name: | Dual specificity protein phosphatase 23 |
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| Synonyms: | DUS23_HUMAN | DUSP23 | Dual specificity protein phosphatase 23 | Dual specificity protein phosphatase 23 (VHZ) | LDP-3 | LDP3 | Low molecular mass dual specificity phosphatase 3 | VH1-like phosphatase Z | VHZ |
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| Type: | Enzyme |
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| Mol. Mass.: | 16592.49 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q9BVJ7 |
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| Residue: | 150 |
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| Sequence: | MGVQPPNFSWVLPGRLAGLALPRLPAHYQFLLDLGVRHLVSLTERGPPHSDSCPGLTLHR
LRIPDFCPPAPDQIDRFVQIVDEANARGEAVGVHCALGFGRTGTMLACYLVKERGLAAGD
AIAEIRRLRPGSIETYEQEKAVFQFYQRTK
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| BDBM50607110 |
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| n/a |
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| Name | BDBM50607110 |
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| Synonyms: | CHEMBL5219519 |
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| Type | Small organic molecule |
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| Emp. Form. | C9H9Br2NO4S |
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| Mol. Mass. | 387.045 |
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| SMILES | Cc1c(Br)cc(NC(=O)CS(O)(=O)=O)cc1Br |
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| Structure | 
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