| Reaction Details |
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 | Report a problem with these data |
| Target | Lysophosphatidic acid receptor 1 |
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| Ligand | BDBM50193518 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_385201 (CHEMBL868013) |
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| Ki | 314±n/a nM |
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| Citation |  Xu, Y; Jiang, G; Tsukahara, R; Fujiwara, Y; Tigyi, G; Prestwich, GD Phosphonothioate and fluoromethylene phosphonate analogues of cyclic phosphatidic acid: Novel antagonists of lysophosphatidic acid receptors. J Med Chem49:5309-15 (2006) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Lysophosphatidic acid receptor 1 |
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| Name: | Lysophosphatidic acid receptor 1 |
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| Synonyms: | EDG2 | LPA receptor 1 | LPA-1 | LPA1 | LPAR1 | LPAR1_HUMAN | Lysophosphatidic acid receptor 1 (LPA1) | Lysophosphatidic acid receptor Edg-2 |
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| Type: | Enzyme |
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| Mol. Mass.: | 41120.55 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q92633 |
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| Residue: | 364 |
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| Sequence: | MAAISTSIPVISQPQFTAMNEPQCFYNESIAFFYNRSGKHLATEWNTVSKLVMGLGITVC
IFIMLANLLVMVAIYVNRRFHFPIYYLMANLAAADFFAGLAYFYLMFNTGPNTRRLTVST
WLLRQGLIDTSLTASVANLLAIAIERHITVFRMQLHTRMSNRRVVVVIVVIWTMAIVMGA
IPSVGWNCICDIENCSNMAPLYSDSYLVFWAIFNLVTFVVMVVLYAHIFGYVRQRTMRMS
RHSSGPRRNRDTMMSLLKTVVIVLGAFIICWTPGLVLLLLDVCCPQCDVLAYEKFFLLLA
EFNSAMNPIIYSYRDKEMSATFRQILCCQRSENPTGPTEGSDRSASSLNHTILAGVHSND
HSVV
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| BDBM50193518 |
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| n/a |
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| Name | BDBM50193518 |
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| Synonyms: | 3-hydroxyl-4-palmitoyloxylbutane 1,3-cyclic phosphonothioate | CHEMBL211465 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H39O4PS |
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| Mol. Mass. | 406.56 |
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| SMILES | CCCCCCCCCCCCCCCC(=O)OCC1CCP(O)(=S)O1 |
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| Structure | 
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