| Reaction Details |
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 | Report a problem with these data |
| Target | Coagulation factor XIII A chain [Q652E] |
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| Ligand | BDBM50164227 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2274760 |
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| IC50 | 100±n/a nM |
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| Citation |  Al-Horani, RA; Kar, S Factor XIIIa inhibitors as potential novel drugs for venous thromboembolism. Eur J Med Chem200:0 (2020) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Coagulation factor XIII A chain [Q652E] |
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| Name: | Coagulation factor XIII A chain [Q652E] |
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| Synonyms: | Coagulation factor XIII A (FXIIIa) | F13A | F13A1 | F13A_HUMAN |
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| Type: | Protein |
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| Mol. Mass.: | 83261.26 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P00488[Q652E] |
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| Residue: | 732 |
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| Sequence: | MSETSRTAFGGRRAVPPNNSNAAEDDLPTVELQGVVPRGVNLQEFLNVTSVHLFKERWDT
NKVDHHTDKYENNKLIVRRGQSFYVQIDFSRPYDPRRDLFRVEYVIGRYPQENKGTYIPV
PIVSELQSGKWGAKIVMREDRSVRLSIQSSPKCIVGKFRMYVAVWTPYGVLRTSRNPETD
TYILFNPWCEDDAVYLDNEKEREEYVLNDIGVIFYGEVNDIKTRSWSYGQFEDGILDTCL
YVMDRAQMDLSGRGNPIKVSRVGSAMVNAKDDEGVLVGSWDNIYAYGVPPSAWTGSVDIL
LEYRSSENPVRYGQCWVFAGVFNTFLRCLGIPARIVTNYFSAHDNDANLQMDIFLEEDGN
VNSKLTKDSVWNYHCWNEAWMTRPDLPVGFGGWQAVDSTPQENSDGMYRCGPASVQAIKH
GHVCFQFDAPFVFAEVNSDLIYITAKKDGTHVVENVDATHIGKLIVTKQIGGDGMMDITD
TYKFQEGQEEERLALETALMYGAKKPLNTEGVMKSRSNVDMDFEVENAVLGKDFKLSITF
RNNSHNRYTITAYLSANITFYTGVPKAEFKKETFDVTLEPLSFKKEAVLIQAGEYMGQLL
EQASLHFFVTARINETRDVLAKQKSTVLTIPEIIIKVRGTQVVGSDMTVTVEFTNPLKET
LRNVWVHLDGPGVTRPMKKMFREIRPNSTVQWEEVCRPWVSGHRKLIASMSSDSLRHVYG
ELDVQIQRRPSM
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| BDBM50164227 |
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| n/a |
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| Name | BDBM50164227 |
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| Synonyms: | 5-Methyl-2-(2-oxo-propylsulfanyl)-thiazolo[2,3-b][1,3,4]thiadiazol-4-ylium; compound with perchlorate | CHEMBL193220 |
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| Type | Small organic molecule |
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| Emp. Form. | C8H9N2OS3 |
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| Mol. Mass. | 245.364 |
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| SMILES | CC(=O)CSc1n[n+]2c(C)csc2s1 |
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| Structure | 
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