| Reaction Details |
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 | Report a problem with these data |
| Target | RNA-binding protein FXR2 |
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| Ligand | BDBM50609019 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2276099 |
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| EC50 | 0.350000±n/a nM |
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| Citation |  Fang, Y; Hegazy, L; Finck, BN; Elgendy, B Recent Advances in the Medicinal Chemistry of Farnesoid X Receptor. J Med Chem64:17545-17571 (2021) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| RNA-binding protein FXR2 |
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| Name: | RNA-binding protein FXR2 |
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| Synonyms: | FMR1 autosomal homolog 2 | FMR1L2 | FXR2 | FXR2P | FXR2_HUMAN | Synonyms=FMR1L2 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 74219.92 |
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| Organism: | Homo sapiens |
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| Description: | ChEMBL_120675 |
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| Residue: | 673 |
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| Sequence: | MGGLASGGDVEPGLPVEVRGSNGAFYKGFVKDVHEDSVTIFFENNWQSERQIPFGDVRLP
PPADYNKEITEGDEVEVYSRANEQEPCGWWLARVRMMKGDFYVIEYAACDATYNEIVTLE
RLRPVNPNPLATKGSFFKVTMAVPEDLREACSNENVHKEFKKALGANCIFLNITNSELFI
LSTTEAPVKRASLLGDMHFRSLRTKLLLMSRNEEATKHLETSKQLAAAFQEEFTVREDLM
GLAIGTHGANIQQARKVPGVTAIELGEETCTFRIYGETPEACRQARSYLEFSEDSVQVPR
NLVGKVIGKNGKVIQEIVDKSGVVRVRVEGDNDKKNPREEGMVPFIFVGTRENISNAQAL
LEYHLSYLQEVEQLRLERLQIDEQLRQIGLGFRPPGSGRGSGGSDKAGYSTDESSSSSLH
ATRTYGGSYGGRGRGRRTGGPAYGPSSDVSTASETESEKREEPNRAGPGDRDPPTRGEES
RRRPTGGRGRGPPPAPRPTSRYNSSSISSVLKDPDSNPYSLLDTSEPEPPVDSEPGEPPP
ASARRRRSRRRRTDEDRTVMDGGLESDGPNMTENGLEDESRPQRRNRSRRRRNRGNRTDG
SISGDRQPVTVADYISRAESQSRQRPPLERTKPSEDSLSGQKGDSVSKLPKGPSENGELS
APLELGSMVNGVS
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| BDBM50609019 |
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| n/a |
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| Name | BDBM50609019 |
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| Synonyms: | CHEMBL5267458 |
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| Type | Small organic molecule |
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| Emp. Form. | C28H23F4N3O5S |
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| Mol. Mass. | 589.558 |
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| SMILES | [H][C@]12CN(c3nc4c(F)cc(cc4s3)C(O)=O)[C@]([H])(C[C@H]1OCc1c(onc1-c1ccccc1OC(F)(F)F)C1CC1)C2 |r| |
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| Structure | 
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