| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Dual specificity protein kinase CLK2 |
|---|
| Ligand | BDBM50609269 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_2277192 |
|---|
| IC50 | 0.822000±n/a nM |
|---|
| Citation |  Qin, Z; Qin, L; Feng, X; Li, Z; Bian, J Development of Cdc2-like Kinase 2 Inhibitors: Achievements and Future Directions. J Med Chem64:13191-13211 (2021) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Dual specificity protein kinase CLK2 |
|---|
| Name: | Dual specificity protein kinase CLK2 |
|---|
| Synonyms: | 2.7.12.1 | CDC-like kinase 2 | CDC-like kinase 2 (CLK2) | CDC2-like kinase 2 (CLK2) | CLK2 | CLK2_HUMAN |
|---|
| Type: | n/a |
|---|
| Mol. Mass.: | 60128.79 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P49760 |
|---|
| Residue: | 499 |
|---|
| Sequence: | MPHPRRYHSSERGSRGSYREHYRSRKHKRRRSRSWSSSSDRTRRRRREDSYHVRSRSSYD
DRSSDRRVYDRRYCGSYRRNDYSRDRGDAYYDTDYRHSYEYQRENSSYRSQRSSRRKHRR
RRRRSRTFSRSSSQHSSRRAKSVEDDAEGHLIYHVGDWLQERYEIVSTLGEGTFGRVVQC
VDHRRGGARVALKIIKNVEKYKEAARLEINVLEKINEKDPDNKNLCVQMFDWFDYHGHMC
ISFELLGLSTFDFLKDNNYLPYPIHQVRHMAFQLCQAVKFLHDNKLTHTDLKPENILFVN
SDYELTYNLEKKRDERSVKSTAVRVVDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSQ
PCDVWSIGCIIFEYYVGFTLFQTHDNREHLAMMERILGPIPSRMIRKTRKQKYFYRGRLD
WDENTSAGRYVRENCKPLRRYLTSEAEEHHQLFDLIESMLEYEPAKRLTLGEALQHPFFA
RLRAEPPNKLWDSSRDISR
|
|
|
|---|
| BDBM50609269 |
|---|
| n/a |
|---|
| Name | BDBM50609269 |
|---|
| Synonyms: | CHEMBL5269810 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C26H27N5O2 |
|---|
| Mol. Mass. | 441.5249 |
|---|
| SMILES | COc1ccc(NC(=O)c2n[nH]c3ccc(cc23)-c2cncc(CN3CCCCC3)c2)cc1 |
|---|
| Structure | 
|
|---|
Search and Browse
