| Reaction Details |
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 | Report a problem with these data |
| Target | M-phase inducer phosphatase 1 |
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| Ligand | BDBM50197855 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_435185 (CHEMBL904571) |
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| IC50 | 6300±n/a nM |
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| Citation |  Brault, L; Denancé, M; Banaszak, E; El Maadidi, S; Battaglia, E; Bagrel, D; Samadi, M Synthesis and biological evaluation of dialkylsubstituted maleic anhydrides as novel inhibitors of Cdc25 dual specificity phosphatases. Eur J Med Chem42:243-7 (2007) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| M-phase inducer phosphatase 1 |
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| Name: | M-phase inducer phosphatase 1 |
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| Synonyms: | CDC25A | Dual specificity phosphatase (Cdc25A) | Dual specificity phosphatase Cdc25A | M-phase inducer phosphatase 1 | MPIP1_HUMAN | phosphatase Cdc25 |
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| Type: | Protein |
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| Mol. Mass.: | 59090.18 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P30304 |
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| Residue: | 524 |
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| Sequence: | MELGPEPPHRRRLLFACSPPPASQPVVKALFGASAAGGLSPVTNLTVTMDQLQGLGSDYE
QPLEVKNNSNLQRMGSSESTDSGFCLDSPGPLDSKENLENPMRRIHSLPQKLLGCSPALK
RSHSDSLDHDIFQLIDPDENKENEAFEFKKPVRPVSRGCLHSHGLQEGKDLFTQRQNSAP
ARMLSSNERDSSEPGNFIPLFTPQSPVTATLSDEDDGFVDLLDGENLKNEEETPSCMASL
WTAPLVMRTTNLDNRCKLFDSPSLCSSSTRSVLKRPERSQEESPPGSTKRRKSMSGASPK
ESTNPEKAHETLHQSLSLASSPKGTIENILDNDPRDLIGDFSKGYLFHTVAGKHQDLKYI
SPEIMASVLNGKFANLIKEFVIIDCRYPYEYEGGHIKGAVNLHMEEEVEDFLLKKPIVPT
DGKRVIVVFHCEFSSERGPRMCRYVRERDRLGNEYPKLHYPELYVLKGGYKEFFMKCQSY
CEPPSYRPMHHEDFKEDLKKFRTKSRTWAGEKSKREMYSRLKKL
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| BDBM50197855 |
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| n/a |
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| Name | BDBM50197855 |
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| Synonyms: | 3-(4-tetradecyl-2,5-dioxo-2,5-dihydrofuran-3-yl)propanoicacid | CHEMBL228418 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H34O5 |
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| Mol. Mass. | 366.4917 |
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| SMILES | CCCCCCCCCCCCCCC1=C(CCC(O)=O)C(=O)OC1=O |c:14| |
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| Structure | 
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