| Reaction Details |
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 | Report a problem with these data |
| Target | Nuclear receptor subfamily 4 group A member 1 |
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| Ligand | BDBM50612665 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2289437 |
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| Kd | 1170±n/a nM |
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| Citation |  Qin, J; Chen, X; Liu, W; Chen, J; Liu, W; Xia, Y; Li, Z; Li, M; Wang, S; Yuan, Q; Qiu, Y; Wu, Z; Fang, M Discovery of 5-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)-1H-indole-2-carboxamide derivatives as novel anti-cancer agents targeting Nur77. Eur J Med Chem244:0 (2022) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Nuclear receptor subfamily 4 group A member 1 |
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| Name: | Nuclear receptor subfamily 4 group A member 1 |
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| Synonyms: | GFRP1 | HMR | NAK1 | NR4A1 | NR4A1_HUMAN | nuclear receptor subfamily 4, group A, member 1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 64467.13 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_27894344 |
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| Residue: | 598 |
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| Sequence: | MPCIQAQYGTPAPSPGPRDHLASDPLTPEFIKPTMDLASPEAAPAAPTALPSFSTFMDGY
TGEFDTFLYQLPGTVQPCSSASSSASSTSSSSATSPASASFKFEDFQVYGCYPGPLSGPV
DEALSSSGSDYYGSPCSAPSPSTPSFQPPQLSPWDGSFGHFSPSQTYEGLRAWTEQLPKA
SGPPQPPAFFSFSPPTGPSPSLAQSPLKLFPSQATHQLGEGESYSMPTAFPGLAPTSPHL
EGSGILDTPVTSTKARSGAPGGSEGRCAVCGDNASCQHYGVRTCEGCKGFFKRTVQKNAK
YICLANKDCPVDKRRRNRCQFCRFQKCLAVGMVKEVVRTDSLKGRRGRLPSKPKQPPDAS
PANLLTSLVRAHLDSGPSTAKLDYSKFQELVLPHFGKEDAGDVQQFYDLLSGSLEVIRKW
AEKIPGFAELSPADQDLLLESAFLELFILRLAYRSKPGEGKLIFCSGLVLHRLQCARGFG
DWIDSILAFSRSLHSLLVDVPAFACLSALVLITDRHGLQEPRRVEELQNRIASCLKEHVA
AVAGEPQPASCLSRLLGKLPELRTLCTQGLQRIFYLKLEDLVPPPPIIDKIFMDTLPF
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| BDBM50612665 |
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| n/a |
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| Name | BDBM50612665 |
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| Synonyms: | CHEMBL5279866 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H18N6O |
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| Mol. Mass. | 406.4393 |
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| SMILES | O=C(N\N=C\c1ccncc1)c1cc2cc(Nc3ccnc4ccccc34)ccc2[nH]1 |
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| Structure | 
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