| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Gag-Pol polyprotein [489-587] |
|---|
| Ligand | BDBM50613804 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_2294250 |
|---|
| Ki | 92±n/a nM |
|---|
| Citation |  Ghosh, AK; Shahabi, D; Kipfmiller, M; Ghosh, AK; Johnson, M; Wang, YF; Agniswamy, J; Amano, M; Weber, IT; Mitsuya, H Evaluation of darunavir-derived HIV-1 protease inhibitors incorporating P2' amide-derivatives: Synthesis, biological evaluation and structural studies. Bioorg Med Chem Lett83:0 (2023) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Gag-Pol polyprotein [489-587] |
|---|
| Name: | Gag-Pol polyprotein [489-587] |
|---|
| Synonyms: | Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol |
|---|
| Type: | Enzyme Subunit |
|---|
| Mol. Mass.: | 10781.16 |
|---|
| Organism: | Human immunodeficiency virus type 1 |
|---|
| Description: | P04585[489-587] |
|---|
| Residue: | 99 |
|---|
| Sequence: | PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
|
|
|
|---|
| BDBM50613804 |
|---|
| n/a |
|---|
| Name | BDBM50613804 |
|---|
| Synonyms: | CHEMBL5287711 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C29H40N4O8S |
|---|
| Mol. Mass. | 604.715 |
|---|
| SMILES | [H][C@@]12CCO[C@]1([H])OC[C@@H]2OC(=O)N[C@@H](Cc1ccccc1)[C@H](O)CN(CC(C)C)S(=O)(=O)c1ccc(NC(=O)CN)cc1 |r| |
|---|
| Structure | 
|
|---|
Search and Browse
